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一例不明原因发热病例:坏死性结节病样肉芽肿病。

A case of fever of unknown origin: necrotizing sarcoid granulomatosis.

作者信息

Unlü G, Onyılmaz T A, Barış S A, Turhan N, Vural C, Başyiğit I, Boyacı H

机构信息

Department of Clinical Microbiology and Infectious Diseases. Haseki Training and Research Hospital, İstanbul.

Departments of Chest Diseases, Faculty of Medicine, University Kocaeli, Turkey.

出版信息

Clin Ter. 2014;165(5):257-60. doi: 10.7417/CT.2014.1756.

Abstract

Necrotizing sarcoid granulomatosis is a rare type of vasculitis; its etiology and pathogenesis are still unknown. The disease primarily affects the lungs, although extra-pulmonary involvement has been reported. The typical symptoms are cough, chest pain, dyspnea, and weight loss; high temperatures have been reported in rare cases. We present the case of a 65-year-old woman who was diagnosed with lymph node tuberculosis, for which she received treatment for six months. The patient experienced no improvement in her symptoms, which included fever, weakness and dyspnea. A re-evaluation of previously collected thoracoscopic biopsy material revealed compatibility with necrotizing sarcoid granulomatosis.

摘要

坏死性结节病样肉芽肿病是一种罕见的血管炎;其病因和发病机制尚不清楚。该疾病主要累及肺部,不过也有肺外受累的报道。典型症状为咳嗽、胸痛、呼吸困难和体重减轻;少数病例有高热的报道。我们报告一例65岁女性病例,该患者曾被诊断为淋巴结结核,并接受了6个月的治疗。患者的症状(包括发热、乏力和呼吸困难)并无改善。对先前采集的胸腔镜活检材料进行重新评估后,发现与坏死性结节病样肉芽肿病相符。

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