Koizumi A, Hashimoto S, Yamamura S, Morishita Y, Abe Y, Majima T, Nemoto N, Kinugawa N, Kawabata Y, Horie T
First Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi. 1997 Aug;35(8):905-9.
A 28-year-old woman was admitted to our hospital because of chest pain. A chest roentgenogram and a chest computed tomogram revealed many nodular shadows on both sides. Examinations of specimens obtained by and by transbronchial lung biopsy during fiberoptic bronchoscopy were not diagnostic, and therefore video thoracoscopic lung biopsy was done. The lung lesion was characterized by aggregates of epithelioid cell granulomas, along with granulomatous and necrotizing angitis. We therefore diagnosed necrotizing sarcoid granulomatosis, and began to administer prednisolone. The nodular shadows disappeared within four weeks. In this case video thoracoscopic lung biopsy was useful in the diagnosis of necrotizing sarcoid granulomatosis in the lung.
一名28岁女性因胸痛入院。胸部X线片和胸部计算机断层扫描显示双侧有许多结节状阴影。纤维支气管镜检查期间经支气管肺活检获取的标本检查未能明确诊断，因此进行了电视胸腔镜肺活检。肺部病变的特征为上皮样细胞肉芽肿聚集，伴有肉芽肿性和坏死性血管炎。因此，我们诊断为坏死性结节病样肉芽肿病，并开始给予泼尼松龙治疗。结节状阴影在四周内消失。在该病例中，电视胸腔镜肺活检对肺部坏死性结节病样肉芽肿病的诊断有用。
