Talafha Abdelsalam Qassem, Ababneh Mohammed Mahmoud, Khalifeh Mohammad Sobhi, Al-Majali Ahmad Mahmoud
Department of Veterinary Clinical Sciences, Faculty of Veterinary Medicine, Jordan University of Science and Technology, P.O. Box 3030, Irbid, 22110, Jordan,
Trop Anim Health Prod. 2015 Feb;47(2):277-83. doi: 10.1007/s11250-014-0716-0. Epub 2014 Nov 5.
The effect of intravaginal fluorogestone acetate (FGA) sponges on prolactin levels (PRL) and correlations between PRL and milk somatic cell count (SCC) and steroid hormones levels of Damascus-local cross goats during transitional period to anestrous were investigated in this study. Fifty-six goats were assigned to three groups. Group 1 (FGA, n = 19) was treated with 40 mg FGA and equine chorionic gonadotropin (600 IU, i.m.) at time of sponge withdrawal (day 0). Group 2 (FGA-PGF; n = 19) was treated similar to group 1 but was also injected with dinoprost tromethamine (naturally occurring PGF2α) (10 mg, i.m.) on day 0. Control goats (n = 18) were left untreated. On day 0, five fertile bucks were turned in with all goats. Milk and blood samples were collected on days -13 (day of sponge insertion), -6, 0, 1, 2, 7, 13, and 20. Prolactin levels were at lowest values on day -13 of the study and increased (p < 0.05) from day -6 to day 20 in all groups. A significant positive correlation (p < 0.05) between PRL and progesterone and between PRL and estradiol levels was found in this study. No significant correlation was found between PRL and SCC of all groups during the study except on days 2 and 20 where PRL levels were correlated (p < 0.05) with SCC of left udder halves of FGA group. In conclusion, estrus induction with FGA resulted in significant increase in PRL. A positive correlation was found between PRL and steroid hormones, but there was no correlation between PRL and goat milk SCC.
本研究调查了阴道内植入醋酸氟孕酮（FGA）海绵对处于过渡到乏情期的大马士革本地杂交山羊催乳素水平（PRL）的影响，以及PRL与乳体细胞计数（SCC）和类固醇激素水平之间的相关性。56只山羊被分为三组。第1组（FGA组，n = 19）在取出海绵时（第0天）用40 mg FGA和马绒毛膜促性腺激素（600 IU，肌肉注射）处理。第2组（FGA - PGF组，n = 19）的处理与第1组相似，但在第0天也注射了氯前列醇（天然存在的PGF2α）（10 mg，肌肉注射）。对照组山羊（n = 18）未接受处理。在第0天，将五只可育公羊放入所有山羊群中。在第 - 13天（插入海绵日）、 - 6、0、1、2、7、13和20天采集牛奶和血液样本。在研究的第 - 13天，催乳素水平处于最低值，所有组从第 - 6天到第20天催乳素水平均升高（p < 0.05）。本研究发现PRL与孕酮以及PRL与雌二醇水平之间存在显著正相关（p < 0.05）。在研究期间，除了第2天和第20天FGA组左半侧乳房的PRL水平与SCC相关（p < 0.05）外，所有组的PRL与SCC之间均未发现显著相关性。总之，FGA诱导发情导致PRL显著升高。PRL与类固醇激素之间存在正相关，但PRL与山羊乳SCC之间无相关性。
