来自五味核果的酚苷。

Phenolic glycosides from Glycosmis pentaphylla.

作者信息

Tian Er-Li, Cui Yuan-Yuan, Yang Guang-Zhong, Mei Zhi-Nan, Chen Yu

机构信息

a College of Chemistry and Materials Science, South Central University for Nationalities , Wuhan 430074 , China.

出版信息

J Asian Nat Prod Res. 2014 Dec;16(12):1119-25. doi: 10.1080/10286020.2014.951924. Epub 2014 Nov 4.

DOI:10.1080/10286020.2014.951924

PMID:25367455

Abstract

Three new phenolic glycosides, named as glycopentosides A-C (1-3), along with nine known compounds were isolated from the n-BuOH extract of stems of Glycosmis pentaphylla. Their structures were determined by using spectroscopic and chemical methods. Bioassay showed that compound 10 (tachioside) could inhibit nitric oxide production in lipopolysaccharides-stimulated RAW 264.7 cells with IC50 value of 12.14 μM.

摘要

从五指毛桃茎的正丁醇提取物中分离得到3个新的酚苷类化合物，命名为戊糖苷A-C（1-3），以及9个已知化合物。通过光谱和化学方法确定了它们的结构。生物活性测试表明，化合物10（塔奇oside）能够抑制脂多糖刺激的RAW 264.7细胞中一氧化氮的产生，IC50值为12.14 μM。