多发性硬化症中年龄、功能与心理困扰的关系。
The relationship of age, function, and psychological distress in multiple sclerosis.
作者信息
Jones Salene M W, Amtmann Dagmar
机构信息
a Group Health Research Institute , Seattle , WA , USA.
出版信息
Psychol Health Med. 2015;20(6):629-34. doi: 10.1080/13548506.2014.979209. Epub 2014 Nov 4.
Age is related to less distress in several populations including people with multiple sclerosis (MS). One theory posits this is due to decreased emotional reactivity and better coping as people age and we attempted to test this theory in MS. We used a cross-sectional survey of 429 people with MS. Participants completed measures of physical and cognitive function, depressive symptoms and anxiety. Age moderated the relationship of physical function to distress, such that decreased physical function was related to more distress in younger participants. Age moderated the relationship of cognitive function to depression, such that decreased cognitive function was related to more depressive symptoms in younger participants. Age did not moderate the relationship of cognitive function and anxiety. The effect was only seen in women with MS; however, there were fewer men in the sample. The results are consistent with the theory of decreased emotional reactivity and better coping with age. However, we were unable to test this in much older adults (75+ years of age).
年龄与包括多发性硬化症（MS）患者在内的多类人群的痛苦减轻有关。一种理论认为，这是由于随着人们年龄增长，情绪反应性降低且应对能力增强，我们试图在MS患者中验证这一理论。我们对429名MS患者进行了横断面调查。参与者完成了身体和认知功能、抑郁症状及焦虑的测量。年龄调节了身体功能与痛苦之间的关系，即身体功能下降在年轻参与者中与更多痛苦相关。年龄调节了认知功能与抑郁之间的关系，即认知功能下降在年轻参与者中与更多抑郁症状相关。年龄并未调节认知功能与焦虑之间的关系。该效应仅在患有MS的女性中可见；然而，样本中的男性较少。研究结果与情绪反应性降低及随年龄增长应对能力增强的理论一致。然而，我们无法在年龄更大的成年人（75岁及以上）中对此进行验证。
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