Muir B R, Rogers D W O
Measurement Science and Standards, National Research Council Canada, 1200 Montreal Road, Ottawa, Ontario K1A 0R6, Canada.
Carleton Laboratory for Radiotherapy Physics, Physics Department, Carleton University, 1125 ColonelBy Drive, Ottawa, Ontario K1S 5B6, Canada.
Med Phys. 2014 Nov;41(11):111701. doi: 10.1118/1.4893915.
To provide a comprehensive investigation of electron beam reference dosimetry using Monte Carlo simulations of the response of 10 plane-parallel and 18 cylindrical ion chamber types. Specific emphasis is placed on the determination of the optimal shift of the chambers' effective point of measurement (EPOM) and beam quality conversion factors.
The EGSnrc system is used for calculations of the absorbed dose to gas in ion chamber models and the absorbed dose to water as a function of depth in a water phantom on which cobalt-60 and several electron beam source models are incident. The optimal EPOM shifts of the ion chambers are determined by comparing calculations of R50 converted from I50 (calculated using ion chamber simulations in phantom) to R50 calculated using simulations of the absorbed dose to water vs depth in water. Beam quality conversion factors are determined as the calculated ratio of the absorbed dose to water to the absorbed dose to air in the ion chamber at the reference depth in a cobalt-60 beam to that in electron beams.
For most plane-parallel chambers, the optimal EPOM shift is inside of the active cavity but different from the shift determined with water-equivalent scaling of the front window of the chamber. These optimal shifts for plane-parallel chambers also reduce the scatter of beam quality conversion factors, kQ, as a function of R50. The optimal shift of cylindrical chambers is found to be less than the 0.5 rcav recommended by current dosimetry protocols. In most cases, the values of the optimal shift are close to 0.3 rcav. Values of kecal are calculated and compared to those from the TG-51 protocol and differences are explained using accurate individual correction factors for a subset of ion chambers investigated. High-precision fits to beam quality conversion factors normalized to unity in a beam with R50 = 7.5 cm (kQ (')) are provided. These factors avoid the use of gradient correction factors as used in the TG-51 protocol although a chamber dependent optimal shift in the EPOM is required when using plane-parallel chambers while no shift is needed with cylindrical chambers. The sensitivity of these results to parameters used to model the ion chambers is discussed and the uncertainty related to the practical use of these results is evaluated.
These results will prove useful as electron beam reference dosimetry protocols are being updated. The analysis of this work indicates that cylindrical ion chambers may be appropriate for use in low-energy electron beams but measurements are required to characterize their use in these beams.
通过对10种平行板型和18种圆柱形电离室类型的响应进行蒙特卡罗模拟,全面研究电子束参考剂量测定。特别强调确定电离室有效测量点(EPOM)的最佳偏移和射束质转换因子。
EGSnrc系统用于计算电离室模型中气体的吸收剂量以及钴 - 60和几种电子束源模型入射的水模体中作为深度函数的水的吸收剂量。通过比较从I50转换的R50(使用模体中的电离室模拟计算)与使用水模体中吸收剂量与深度模拟计算的R50来确定电离室的最佳EPOM偏移。射束质转换因子确定为在钴 - 60射束的参考深度处水的吸收剂量与电离室中空气的吸收剂量之比与电子束中该比值的计算值。
对于大多数平行板电离室,最佳EPOM偏移在有效腔内,但不同于通过电离室前窗的水等效缩放确定的偏移。这些平行板电离室的最佳偏移也减少了射束质转换因子kQ随R50的散射。发现圆柱形电离室的最佳偏移小于当前剂量测定协议推荐的0.5rcav。在大多数情况下,最佳偏移值接近0.3rcav。计算kecal值并与TG - 51协议的值进行比较,并使用所研究的一部分电离室的精确个体校正因子解释差异。提供了在R50 = 7.5 cm的射束中归一化为1的射束质转换因子的高精度拟合(kQ('))。这些因子避免了使用TG - 51协议中使用的梯度校正因子,尽管使用平行板电离室时需要在EPOM中进行依赖于电离室的最佳偏移,而使用圆柱形电离室时不需要偏移。讨论了这些结果对用于模拟电离室的参数的敏感性,并评估了与这些结果实际应用相关的不确定性。
随着电子束参考剂量测定协议的更新,这些结果将被证明是有用的。这项工作的分析表明,圆柱形电离室可能适用于低能电子束,但需要进行测量以表征它们在这些射束中的使用情况。