Sohn Sung Yun, Kang Jee In, Namkoong Kee, Kim Se Joo
Department of Psychiatry and Institute of Behavioral Science in Medicine, Yonsei University College of Medicine, Seoul, Korea.
PLoS One. 2014 Nov 5;9(11):e111739. doi: 10.1371/journal.pone.0111739. eCollection 2014.
Although the relationship between obsessive compulsive disorder (OCD) and impulsivity has long been debated, impulsivity has not been systematically examined in clinical samples of OCD. Meanwhile, recent findings suggest that impulsivity is multi-dimensional construct that can be examined through several constructs. Therefore, this study is aimed to evaluate multiple facets of impulsivity in OCD.
The recruitment includes 80 OCD and 76 healthy control participants. Participants completed a test battery comprising three behavioral tasks of stop signal task (SST), delay discounting task (DDT) and balloon analog risk test (BART), and one self-report measure of the Barratt Impulsiveness scale (BIS-11).
OCD subjects showed significantly lower stop signal reaction time of SST reflecting higher action impulsivity and higher delay discounting parameter of DDT suggesting increased choice impulsivity but significantly lower adjusted mean pump of BART implying lower risk taking propensity of BART than healthy control.
Increased Action and choice impulsivity, and decreased risk taking propensities were found in OCD. These findings seem to be consistent with clinical characteristics of OCD such as greater preference for or avoid risky situations (avoidance), inability to wait tension relief may provoke safety behaviors (compulsion) and inability to stop already started behaviors (repetition).
尽管强迫症(OCD)与冲动性之间的关系长期以来一直存在争议,但冲动性尚未在强迫症的临床样本中得到系统研究。同时,最近的研究结果表明,冲动性是一个多维结构,可以通过几种结构来进行研究。因此,本研究旨在评估强迫症中冲动性的多个方面。
招募了80名强迫症患者和76名健康对照参与者。参与者完成了一组测试,包括停止信号任务(SST)、延迟折扣任务(DDT)和气球模拟风险测试(BART)这三项行为任务,以及一项关于巴拉特冲动性量表(BIS - 11)的自我报告测量。
强迫症患者在SST中的停止信号反应时间显著缩短,这反映出其较高的行动冲动性;在DDT中延迟折扣参数较高,表明选择冲动性增加;但在BART中调整后的平均打气量显著较低,这意味着与健康对照相比,其在BART中的冒险倾向较低。
在强迫症患者中发现行动和选择冲动性增加,冒险倾向降低。这些发现似乎与强迫症的临床特征一致,例如对危险情况有更大的偏好或回避(回避)、无法等待紧张缓解可能引发安全行为(强迫)以及无法停止已经开始的行为(重复)。