Martin Staci, Nelson Schmitt Shawn, Wolters Pamela L, Abel Brittany, Toledo-Tamula Mary Anne, Baldwin Andrea, Wicksell Rikard K, Merchant Melinda, Widemann Brigitte
National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
Pain Med. 2015 Feb;16(2):367-73. doi: 10.1111/pme.12620. Epub 2014 Nov 6.
Measurement of pain interference in children is challenged by a lack of validated measures with a parent proxy report. This study investigated the psychometric properties of the Pain Interference Index (PII), a six-item questionnaire originally developed in Swedish, in chronically ill youth.
We adapted the PII for English-speaking participants and created a parallel parent proxy measure. Respondents indicate how much pain has interfered with the child's life in the past 2 weeks (0-6 scale); higher scores indicate more pain interference. Eligible participants included individuals 6-25 years with neurofibromatosis type 1 (NF1) and cancer. Internal consistency was assessed; validity was examined by correlating PII scores with existing measures of pain interference (Modified Brief Pain Inventory [MBPI]) and pain intensity (visual analogue scale [VAS]), and with measures of disease severity.
Among 60 participants (mean age 14.7 years, range 6-24) and their parents, PII internal consistency was 0.84 and 0.96, respectively. PII scores correlated with MBPI (r = 0.81, P < 0.0001) and VAS (r = 0.55, P < 0.0001) scores and differentiated between patients with mild vs moderate/severe NF1 disease severity (P < 0.05). The PII-Parent was significantly correlated with the mothers' and fathers' VAS rating of the child's pain intensity (Ps < 0.01).
Internal consistency of the English PII is high; validity is supported by the PII's correlations with other measures of pain interference and pain intensity, and with disease severity in patients with NF1. Preliminary data indicate that the English PII is a reliable, valid, feasible pain interference measure for youth with NF1 and cancer.
由于缺乏经过验证的家长代理报告测量方法，儿童疼痛干扰的测量面临挑战。本研究调查了疼痛干扰指数（PII）的心理测量特性，该指数是一份最初用瑞典语编制的六项问卷，用于慢性病青少年。
我们对PII进行了改编，使其适用于说英语的参与者，并创建了一个平行的家长代理测量方法。受访者指出在过去2周内疼痛对孩子生活的干扰程度（0 - 6分制）；分数越高表明疼痛干扰越大。符合条件的参与者包括6 - 25岁的1型神经纤维瘤病（NF1）患者和癌症患者。评估了内部一致性；通过将PII分数与现有的疼痛干扰测量方法（改良简短疼痛量表[MBPI]）、疼痛强度测量方法（视觉模拟量表[VAS]）以及疾病严重程度测量方法进行相关性分析来检验有效性。
在60名参与者（平均年龄14.7岁，范围6 - 24岁）及其父母中，PII的内部一致性分别为0.84和0.96。PII分数与MBPI（r = 0.81，P < 0.0001）和VAS（r = 0.55，P < 0.0001）分数相关，并且在轻度与中度/重度NF1疾病严重程度的患者之间存在差异（P < 0.05）。PII - 家长版与母亲和父亲对孩子疼痛强度的VAS评分显著相关（P < 0.01）。
英语版PII的内部一致性较高；PII与其他疼痛干扰和疼痛强度测量方法以及NF1患者的疾病严重程度之间的相关性支持了其有效性。初步数据表明，英语版PII是一种可靠、有效且可行的用于NF1和癌症青少年的疼痛干扰测量方法。
