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会议论文集:致衰弱性眼病

Proceedings: debilitating eye diseases.

作者信息

Caras Ingrid W, Littman Neil, Abo Arie

机构信息

California Institute for Regenerative Medicine, San Francisco, California, USA

California Institute for Regenerative Medicine, San Francisco, California, USA.

出版信息

Stem Cells Transl Med. 2014 Dec;3(12):1393-7. doi: 10.5966/sctm.2014-0221. Epub 2014 Nov 6.

DOI:10.5966/sctm.2014-0221
PMID:25378652
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4250220/
Abstract

Debilitating eye diseases such as age-related macular degeneration and retinitis pigmentosa currently represent a large unmet medical need that could potentially be addressed by stem cell therapy. A number of novel stem cell-based cellular therapies are now under development to treat a variety of eye diseases. The approaches being taken by the California Institute for Regenerative Medicine, together with its grantees, are discussed.

摘要

诸如年龄相关性黄斑变性和色素性视网膜炎等使人衰弱的眼部疾病,目前存在着巨大的尚未满足的医疗需求,而干细胞疗法有可能解决这一问题。目前正在开发一些基于新型干细胞的细胞疗法来治疗各种眼部疾病。本文将讨论加利福尼亚再生医学研究所及其受资助者所采用的方法。

相似文献

1
Proceedings: debilitating eye diseases.会议论文集:致衰弱性眼病
Stem Cells Transl Med. 2014 Dec;3(12):1393-7. doi: 10.5966/sctm.2014-0221. Epub 2014 Nov 6.
2
Gene and Induced Pluripotent Stem Cell Therapy for Retinal Diseases.基因和诱导多能干细胞治疗视网膜疾病。
Annu Rev Genomics Hum Genet. 2019 Aug 31;20:201-216. doi: 10.1146/annurev-genom-083118-015043. Epub 2019 Apr 24.
3
Quality of life in patients with retinitis pigmentosa submitted to intravitreal use of bone marrow-derived stem cells (Reticell -clinical trial).接受玻璃体内注射骨髓源性干细胞的视网膜色素变性患者的生活质量(Reticell - 临床试验)
Stem Cell Res Ther. 2015 Mar 14;6(1):29. doi: 10.1186/s13287-015-0020-6.
4
A stem cell journey in ophthalmology: From the bench to the clinic.眼科学中的干细胞之旅:从实验室到临床。
Stem Cells Transl Med. 2021 Dec;10(12):1581-1587. doi: 10.1002/sctm.21-0239. Epub 2021 Sep 13.
5
Gene and Cell Therapies: Inserm at the Heart of Biomedical Revolutions.基因与细胞疗法:法国国家健康与医学研究院处于生物医学革命的核心地位。
Hum Gene Ther. 2016 Feb;27(2):98-9. doi: 10.1089/hum.2016.29021.yle.
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Recent advances of stem cell therapy for retinitis pigmentosa.视网膜色素变性干细胞治疗的最新进展
Int J Mol Sci. 2014 Aug 20;15(8):14456-74. doi: 10.3390/ijms150814456.
7
Steady advance of stem cell therapies: report from the 2011 World Stem Cell Summit, Pasadena, California, October 3-5.干细胞疗法的稳步进展:2011 年世界干细胞峰会报告,加利福尼亚州帕萨迪纳,10 月 3 日至 5 日。
Rejuvenation Res. 2011 Dec;14(6):699-704. doi: 10.1089/rej.2011.1292.
8
Bone marrow-derived stem cells preserve cone vision in retinitis pigmentosa.骨髓源性干细胞可保留视网膜色素变性患者的视锥细胞视觉。
J Clin Invest. 2004 Sep;114(6):755-7. doi: 10.1172/JCI22930.
9
RPGR and RP2: targets for the treatment of X-linked retinitis pigmentosa?RPGR和RP2:治疗X连锁视网膜色素变性的靶点?
Expert Opin Ther Targets. 2009 Oct;13(10):1239-51. doi: 10.1517/14728220903225016.
10
[Filatov therapy of retinitis pigmentosa; remote results and experimental study].
Boll Ocul. 1953 Mar;32(3):134-46.

引用本文的文献

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Multiple consecutive-biphasic pulse stimulation improves spatially localized firing of retinal ganglion cells in the degenerate retina.多次连续双相脉冲刺激可改善退化视网膜中视网膜神经节细胞的空间局部放电。
Korean J Physiol Pharmacol. 2023 Nov 1;27(6):541-553. doi: 10.4196/kjpp.2023.27.6.541.
2
High amplitude pulses on the same charge condition efficiently elicit bipolar cell-mediated retinal ganglion cell responses in the degenerate retina.在相同电荷条件下的高幅度脉冲能有效引发退化视网膜中双极细胞介导的视网膜神经节细胞反应。
Biomed Eng Lett. 2023 Jan 31;13(2):129-140. doi: 10.1007/s13534-023-00260-4. eCollection 2023 May.
3
High-Density EEG in a Charles Bonnet Syndrome Patient during and without Visual Hallucinations: A Case-Report Study.《伴有和不伴有视觉幻觉的 Charles Bonnet 综合征患者的高密度脑电图:一项病例报告研究》。
Cells. 2021 Aug 5;10(8):1991. doi: 10.3390/cells10081991.
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Resting-state functional connectivity and cortical thickness characterization of a patient with Charles Bonnet syndrome.静止状态功能连接和皮质厚度特征分析一位查尔斯·邦纳综合征患者。
PLoS One. 2019 Jul 18;14(7):e0219656. doi: 10.1371/journal.pone.0219656. eCollection 2019.
5
Let There Be Light: Gene and Cell Therapy for Blindness.让光明重现:失明的基因与细胞疗法
Hum Gene Ther. 2016 Feb;27(2):134-47. doi: 10.1089/hum.2015.147.
6
Current status of pluripotent stem cells: moving the first therapies to the clinic.多能干细胞的现状:将首批疗法推向临床。
Nat Rev Drug Discov. 2015 Oct;14(10):681-92. doi: 10.1038/nrd4738. Epub 2015 Sep 22.

本文引用的文献

1
Retinal stem cells and potential cell transplantation treatments.视网膜干细胞与潜在的细胞移植治疗
J Chin Med Assoc. 2014 Nov;77(11):556-61. doi: 10.1016/j.jcma.2014.08.001. Epub 2014 Sep 18.
2
Eyes on the prize: limbal stem cells and corneal restoration.关注目标:角膜缘干细胞与角膜修复。
Cell Stem Cell. 2014 Aug 7;15(2):121-2. doi: 10.1016/j.stem.2014.07.011.
3
A three-dimensional culture method to expand limbal stem/progenitor cells.一种三维培养方法以扩增角膜缘干细胞/祖细胞。
Tissue Eng Part C Methods. 2014 May;20(5):393-400. doi: 10.1089/ten.TEC.2013.0246. Epub 2013 Nov 7.
4
Limbal stem-cell therapy and long-term corneal regeneration.角膜缘干细胞治疗与长期角膜再生。
N Engl J Med. 2010 Jul 8;363(2):147-55. doi: 10.1056/NEJMoa0905955. Epub 2010 Jun 23.
5
Prevalence of age-related macular degeneration in the United States.美国年龄相关性黄斑变性的患病率。
Arch Ophthalmol. 2004 Apr;122(4):564-72. doi: 10.1001/archopht.122.4.564.
6
One year follow up of macular translocation with 360 degree retinotomy in patients with age related macular degeneration.年龄相关性黄斑变性患者行360度视网膜切开术黄斑转位术的一年随访
Br J Ophthalmol. 2003 May;87(5):615-21. doi: 10.1136/bjo.87.5.615.