儿科静脉注射免疫球蛋白：综述
Intravenous immunoglobulin in pediatrics: A review.
作者信息
Prasad A N, Chaudhary Sanjay
机构信息
Classified Specialist (Pediatrics), Command Hospital (Western Command), Chandimandir, Panchkula 134107, Haryana, India.
出版信息
Med J Armed Forces India. 2014 Jul;70(3):277-80. doi: 10.1016/j.mjafi.2013.05.011. Epub 2013 Aug 6.
Abstract
There has been a rapid expansion of the use of intravenous immunoglobulin (IVIG) for an ever-growing number of conditions. IVIG is used at a 'replacement dose' (400-600 mg/kg/month) in antibody deficiencies and is used at a high dose (2 g/kg) as an 'immunomodulatory' agent in an increasing number of immune and inflammatory disorders.(1) The limitations for IVIG are the cost of the preparation and the need for intravenous infusions. Due to the cost, shortages and growing use of IVIG there have been attempts to develop evidence-based guidelines for the use of IVIG in a wide variety of immune disorders in children and neonates. This commentary provides the recommendations and recent publication regarding the use of IVIG in various conditions in children.
摘要
静脉注射免疫球蛋白（IVIG）在越来越多病症中的使用迅速增加。在抗体缺乏症中，IVIG以“替代剂量”（400 - 600毫克/千克/月）使用，而在越来越多的免疫和炎症性疾病中，它以高剂量（2克/千克）作为“免疫调节剂”使用。（1）IVIG的局限性在于制剂成本和静脉输注的需求。由于成本、短缺以及IVIG使用的增加，人们尝试为儿童和新生儿各种免疫疾病中IVIG的使用制定循证指南。本评论提供了关于IVIG在儿童各种病症中使用的建议和近期出版物。
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