Schulz G E, Schirmer R H, Sachsenheimer W, Pai E F
Nature. 1978 May 11;273(5658):120-4. doi: 10.1038/273120a0.
The three-dimensional structure of the dimeric flavoenzyme glutathione reductase from human erythrocytes has been elucidated by an X-ray diffraction analysis at 0.3 nm resolution. The polypeptide chain has been traced, and the binding positions of FAD, NADP and glutathione have been determined. A mechanism for the electron transfer is discussed.
通过分辨率为0.3纳米的X射线衍射分析,已阐明了来自人类红细胞的二聚体黄素酶谷胱甘肽还原酶的三维结构。已追踪了多肽链,并确定了FAD、NADP和谷胱甘肽的结合位置。讨论了电子转移的机制。