Sachdev Nishant, Gupta Pawan, Singh Ramandeep, Chakrabarti Arunaloke, Gupta Vishali, Gupta Amod
From the Departments of *Ophthalmology and †Microbiology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Retin Cases Brief Rep. 2010 Winter;4(1):14-7. doi: 10.1097/ICB.0b013e318196b26c.
To report a case of bilateral endogenous Aspergillus endophthalmitis in an immunocompetent patient.
We report a young immunocompetent 26-year-old Indian woman who presented with bilateral simultaneous endogenous endophthalmitis and was managed with pars plana vitreous surgery in both the eyes.
Smear examination of the vitrectomy specimen from the left eye identified septate hyphae with acute-angle branching, which on culture showed growth of Aspergillus fumigatus. A detailed systemic evaluation failed to reveal any systemic focus or predisposing factor for fungal infection. The patient had received an intravenous dextrose infusion 2 weeks before this episode while being treated at a rural hospital for malarial infection. During follow-up, she developed bilateral rhegmatogenous retinal detachment requiring revised pars plana vitreous surgery with silicon oil tamponade.
An immunocompetent patient can present with bilateral simultaneous endogenous Aspergillus endophthalmitis after receiving an intravenous infusion of presumably contaminated dextrose solution.