Hughes Edward H, Hunyor Alex P, Gorbatov Mark, Ho I-van
From the Retinal Department, Sydney Eye Hospital, Sydney, New South Wales, Australia.
Retin Cases Brief Rep. 2012 Winter;6(1):19-21. doi: 10.1097/ICB.0b013e3181f7f7ee.
To report a case of visual loss immediately after hand, foot, and mouth disease and demonstrate the high-resolution optical coherence tomography findings.
A retrospective case report of a 19-year-old nursery worker with resolving hand, foot, and mouth disease and acute unilateral visual loss.
The clinical features were characteristic of unilateral acute idiopathic maculopathy. High-resolution optical coherence tomography demonstrated highly reflective subretinal material at the macula of one eye with disruption of the photoreceptor inner segment/outer segment junction. Vision remained poor for 4 weeks when there was rapid recovery coinciding with reconstitution of the inner segment/outer segment junction on optical coherence tomography.
Unilateral acute idiopathic maculopathy may be caused by Coxsackievirus infection. Optical coherence tomography and clinical findings suggest an acute viral retinal pigment epitheliitis to be the main pathologic feature.
报告1例手足口病后立即出现视力丧失的病例，并展示高分辨率光学相干断层扫描结果。
对1例19岁托儿所工作人员的回顾性病例报告，该患者手足口病症状正在消退，同时出现急性单侧视力丧失。
临床特征符合单侧急性特发性黄斑病变。高分辨率光学相干断层扫描显示一只眼睛黄斑处有高反射性视网膜下物质，光感受器内节/外节连接中断。视力在4周内一直很差，之后随着光学相干断层扫描显示内节/外节连接恢复，视力迅速恢复。
单侧急性特发性黄斑病变可能由柯萨奇病毒感染引起。光学相干断层扫描和临床结果提示急性病毒性视网膜色素上皮炎是主要病理特征。
