Affortit-Demoge Aude, Querques Giuseppe, Angulo-Bocco Cecilia, DʼAthis Philippe, Soubrane Gisele, Souied Eric H
From the *Department of Ophthalmology, University of Paris XII, Centre Hospitalier Intercommunal de Creteil, Creteil, France; and the †Department of Ophthalmology, Ospedali Riuniti, University of Foggia, Foggia, Italy.
Retin Cases Brief Rep. 2009 Spring;3(2):180-2. doi: 10.1097/ICB.0b013e31816bbee9.
To describe the optical coherence tomography (OCT) features of X-linked choroideremia (CHM).
Prospective, observational case series.
Color fundus photography, fluorescein angiography, indocyanine green angiography, and OCT were performed for four patients (eight eyes) with CHM.
In areas of angiographic choriocapillaris loss, OCT revealed retinal thinning (mean, 124 μm [range, 97-150 μm) and increased reflectivity of the choroid. On the contrary, in areas of preserved choriocapillaris, retinal thickness was within normal limits (mean, 256 μm [range, 238-284 μm]; P < 0.001).
OCT revealed a correlation between retinal thickness and choriocapillaris preservation in CHM.
描述X连锁遗传性视网膜脉络膜萎缩（CHM）的光学相干断层扫描（OCT）特征。
前瞻性观察性病例系列。
对4例（8只眼）CHM患者进行了彩色眼底照相、荧光素血管造影、吲哚菁绿血管造影和OCT检查。
在脉络膜毛细血管造影显示缺失的区域，OCT显示视网膜变薄（平均124μm[范围97 - 150μm]），脉络膜反射率增加。相反，在脉络膜毛细血管保留的区域，视网膜厚度在正常范围内（平均256μm[范围238 - 284μm]；P < 0.001）。
OCT显示CHM患者视网膜厚度与脉络膜毛细血管保留之间存在相关性。
