睡眠中电持续状态癫痫患者多通道脑电图的全局同步化
Global Synchronization of Multichannel EEG in Patients With Electrical Status Epilepticus in Sleep.
作者信息
Ouyang Gaoxiang, Wang Yinghua, Yang Zhixian, Li Xiaoli
机构信息
State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, China Center for Collaboration and Innovation in Brain and Learning Sciences, Beijing Normal University, Beijing, China.
Department of Pediatrics, Peking University First Hospital, Beijing, China
出版信息
Clin EEG Neurosci. 2015 Oct;46(4):357-63. doi: 10.1177/1550059414538807. Epub 2014 Nov 11.
In the research field of epilepsy, it is a challenge to understand the transition of brain activity to electrical status epilepticus in sleep (ESES). In this study, an S-estimator method is proposed to describe the course of global synchronization in multichannel electroencephalograph (EEG) from awake to sleep in 11 patients with ESES. The study confirms that there is a significant increase in spikes and global synchronization from awake to sleep. It is also found that global synchronization is strongly correlated with spikes. The proposed method has the potential of revealing the intrinsic features of EEG signals and the underlying brain dynamics in ESES.
在癫痫研究领域，理解睡眠中脑活动向癫痫电持续状态（ESES）的转变是一项挑战。在本研究中，提出了一种S估计器方法来描述11例ESES患者从清醒到睡眠过程中多通道脑电图（EEG）的全局同步过程。该研究证实，从清醒到睡眠，棘波和全局同步有显著增加。还发现全局同步与棘波密切相关。所提出的方法具有揭示ESES中EEG信号的内在特征和潜在脑动力学的潜力。
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