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贲门失弛缓症行Heller肌切开术后Dor术式与Toupet术式的生活质量比较

Quality of life comparing dor and toupet after heller myotomy for achalasia.

作者信息

Tomasko Jonathan M, Augustin Toms, Tran Tung T, Haluck Randy S, Rogers Ann M, Lyn-Sue Jerome R

机构信息

Department of Surgery, Division of Minimally Invasive/Bariatric Surgery, Penn State Milton S. Hershey Medical Center, Hershey, PA, USA.

出版信息

JSLS. 2014 Jul-Sep;18(3). doi: 10.4293/JSLS.2014.00191.

Abstract

BACKGROUND

Laparoscopic Heller cardiomyotomy (LHC) is standard therapy for achalasia. Traditionally, an antireflux procedure has accompanied the myotomy. This study was undertaken to compare quality-of-life outcomes between patients undergoing myotomy with Toupet versus Dor fundoplication. In addition, we investigated overall patient satisfaction after LHC in the treatment of achalasia.

METHODS

One hundred thirty-five patients who underwent LHC over a 13-year period were identified for inclusion. Symptoms queried included dysphagia, heartburn, and bloating using the Gastroesophageal Reflux Disease-Health-Related Quality of Life Scale and a second published scale for the assessment of gastroesophageal reflux disease and dysphagia symptoms. The patients' overall satisfaction after surgery was also rated. Data were compared on the basis of type of fundoplication. Symptom scores were analyzed using chi-square tests and Fisher's exact tests.

RESULTS

Sixty-three patients completed the survey (47%). There were no perioperative deaths or reoperations. The mean length of stay was 2.8 days. The mean operative time for LHC with Toupet fundoplication was 137.3±30.91 minutes and for LHC with Dor fundoplication was 111.5±32.44 minutes (P=.006). There was no difference with respect to the incidence or severity of postoperative heartburn, dysphagia, or bloating. Overall satisfaction with Toupet fundoplication was 87.5% and with Dor fundoplication was 93.8% (P>.999).

CONCLUSIONS

LHC with either Toupet or Dor fundoplication gave excellent patient satisfaction. Postoperative symptoms of heartburn and dysphagia were equivalent when comparing LHC with either antireflux procedure. Dor and Toupet fundoplication were found to have equivalent outcomes in the short term. We prefer Dor to Toupet fundoplication because of its decreased need for extensive dissection and better mucosal protection.

摘要

背景

腹腔镜下贲门肌层切开术(LHC)是贲门失弛缓症的标准治疗方法。传统上,肌层切开术会同时进行抗反流手术。本研究旨在比较接受杜氏(Toupet)胃底折叠术与 Dor 胃底折叠术的肌层切开术患者的生活质量结果。此外,我们调查了腹腔镜下贲门肌层切开术治疗贲门失弛缓症后患者的总体满意度。

方法

确定 135 例在 13 年期间接受腹腔镜下贲门肌层切开术的患者纳入研究。使用胃食管反流病健康相关生活质量量表以及另一个已发表的用于评估胃食管反流病和吞咽困难症状的量表询问症状,包括吞咽困难、烧心和腹胀。还对患者术后的总体满意度进行评分。根据胃底折叠术的类型比较数据。使用卡方检验和 Fisher 精确检验分析症状评分。

结果

63 例患者完成了调查(47%)。无围手术期死亡或再次手术。平均住院时间为 2.8 天。接受杜氏胃底折叠术的腹腔镜下贲门肌层切开术的平均手术时间为 137.3±30.91 分钟,接受 Dor 胃底折叠术的为 111.5±32.44 分钟(P = 0.006)。术后烧心、吞咽困难或腹胀的发生率及严重程度无差异。杜氏胃底折叠术的总体满意度为 87.5%,Dor 胃底折叠术为 93.8%(P>0.999)。

结论

杜氏或 Dor 胃底折叠术的腹腔镜下贲门肌层切开术患者满意度高。比较腹腔镜下贲门肌层切开术与任何一种抗反流手术时,术后烧心和吞咽困难症状相当。发现 Dor 和杜氏胃底折叠术在短期内效果相当。由于其对广泛解剖的需求减少且黏膜保护更好,我们更倾向于 Dor 胃底折叠术而非杜氏胃底折叠术。

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