Department of Surgery, Kitasato University School of Medicine, 2-1-1, Asamizodai, Minami-ku, Sagamihara, Kanagawa, 252-0380, Japan,
Surg Today. 2014 Apr;44(4):732-9. doi: 10.1007/s00595-013-0640-3. Epub 2013 Jun 22.
We compared the outcomes of Toupet fundoplication with those of Dor fundoplication in patients with achalasia who underwent laparoscopic Heller myotomy.
Seventy-two patients with achalasia and dysphagia underwent laparoscopic Heller myotomy with fundoplication performed by a single surgeon. Heller-Toupet fundoplication (HT) was performed in 30 patients, and Heller-Dor fundoplication (HD) was done in 42. The symptoms and esophageal function were retrospectively assessed in both groups.
The dysphagia scores significantly decreased after both the HT and HD procedures, and did not differ significantly between them. The incidence of reflux symptoms was significantly higher after HT (26.7%) than after HD (7.1%). The lower esophageal sphincter (LES) resting pressure significantly decreased after both HT and HD. Upon endoscopic examination, the incidence of reflux esophagitis was significantly higher after HT (38.5%) than after HD (8.8%). During esophageal pH monitoring, the fraction time at pH <4 was similar in the patients who underwent HT and HD.
Laparoscopic Heller myotomy provided significant improvements in the dysphagia symptoms of achalasia patients, regardless of the type of fundoplication. The incidences of reflux symptoms and reflux esophagitis were higher after HT than after HD. However, the results of pH monitoring did not differ between the procedures.
我们比较了腹腔镜 Heller 肌切开术联合 Toupet 胃底折叠术与 Dor 胃底折叠术治疗贲门失弛缓症患者的疗效。
72 例贲门失弛缓症伴吞咽困难患者由同一位外科医生行腹腔镜 Heller 肌切开术加抗反流手术。其中 30 例行 Heller-Toupet 胃底折叠术(HT),42 例行 Heller-Dor 胃底折叠术(HD)。回顾性评估两组患者的症状和食管功能。
HT 和 HD 术后吞咽困难评分均显著降低,两组间无显著差异。HT 术后反流症状发生率(26.7%)显著高于 HD 术后(7.1%)。HT 和 HD 术后食管下括约肌(LES)静息压均显著降低。内镜检查发现,HT 术后反流性食管炎发生率(38.5%)显著高于 HD 术后(8.8%)。食管 pH 监测显示,HT 和 HD 术后 pH<4 的时间分数相似。
腹腔镜 Heller 肌切开术可显著改善贲门失弛缓症患者的吞咽困难症状,与胃底折叠术的类型无关。HT 术后反流症状和反流性食管炎的发生率高于 HD 术后,但 pH 监测结果无差异。