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J Gastrointest Surg. 2020 Mar;24(3):505-515. doi: 10.1007/s11605-019-04465-w. Epub 2019 Dec 17.
2
Endoscopic or Surgical Myotomy in Patients with Idiopathic Achalasia.特发性贲门失弛缓症患者的内镜或手术肌切开术。
N Engl J Med. 2019 Dec 5;381(23):2219-2229. doi: 10.1056/NEJMoa1905380.
3
Case of early Barrett cancer following peroral endoscopic myotomy.经口内镜下肌切开术后早期巴雷特食管癌病例
Gut. 2019 Dec;68(12):2107-2110. doi: 10.1136/gutjnl-2019-318950. Epub 2019 Jul 29.
4
Effect of Peroral Endoscopic Myotomy vs Pneumatic Dilation on Symptom Severity and Treatment Outcomes Among Treatment-Naive Patients With Achalasia: A Randomized Clinical Trial.经口内镜肌切开术与气囊扩张治疗原发性贲门失弛缓症患者的疗效比较:一项随机临床试验。
JAMA. 2019 Jul 9;322(2):134-144. doi: 10.1001/jama.2019.8859.
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A Thousand and One Laparoscopic Heller Myotomies for Esophageal Achalasia: a 25-Year Experience at a Single Tertiary Center.一千零一次腹腔镜 Heller 肌切开术治疗食管失弛缓症:单中心 25 年经验。
J Gastrointest Surg. 2019 Jan;23(1):23-35. doi: 10.1007/s11605-018-3956-x. Epub 2018 Sep 20.
6
The 2018 ISDE achalasia guidelines.2018年国际吞咽障碍食管动力学会贲门失弛缓症指南。
Dis Esophagus. 2018 Sep 1;31(9). doi: 10.1093/dote/doy071.
7
Whose patient is it? The path to multidisciplinary management of achalasia.这是谁的病人?贲门失弛缓症的多学科管理之路。
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贲门失弛缓症的外科治疗

Surgical management of achalasia.

作者信息

Nurczyk Kamil, Patti Marco G

机构信息

Department of Surgery University of North Carolina at Chapel Hill Chapel Hill NC USA.

2nd Department of General and Gastrointestinal Surgery, and Surgical Oncology of the Alimentary Tract Medical University of Lublin Lublin Poland.

出版信息

Ann Gastroenterol Surg. 2020 May 25;4(4):343-351. doi: 10.1002/ags3.12344. eCollection 2020 Jul.

DOI:10.1002/ags3.12344
PMID:32724877
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7382425/
Abstract

Esophageal achalasia is a primary esophageal motility disorder characterized by lack of peristalsis and by incomplete or absent relaxation of the lower esophageal sphincter in response to swallowing. The cause of the disease is unknown. The goal of treatment is to eliminate the functional outflow obstruction at the level of the gastroesophageal junction, therefore allowing emptying of the esophagus into the stomach. They include the laparoscopic Heller myotomy with partial fundoplication, pneumatic dilatation, and peroral endoscopic myotomy. Esophagectomy is considered as a last resort for patients who have failed prior therapeutic attempts. In this evidence and experience-based review, we will illustrate the technique and results of the surgical treatment of esophageal achalasia and compare it to the other available treatment modalities.

摘要

贲门失弛缓症是一种原发性食管动力障碍性疾病,其特征为缺乏蠕动,且吞咽时食管下括约肌松弛不完全或无松弛。该病病因不明。治疗目标是消除胃食管交界处的功能性流出道梗阻,从而使食管能够排空至胃内。治疗方法包括腹腔镜下Heller肌切开术加部分胃底折叠术、气囊扩张术和经口内镜下肌切开术。对于先前治疗尝试失败的患者,食管切除术被视为最后的治疗手段。在这篇基于证据和经验的综述中,我们将阐述贲门失弛缓症手术治疗的技术和结果,并将其与其他可用的治疗方式进行比较。