Nurczyk Kamil, Patti Marco G
Department of Surgery University of North Carolina at Chapel Hill Chapel Hill NC USA.
2nd Department of General and Gastrointestinal Surgery, and Surgical Oncology of the Alimentary Tract Medical University of Lublin Lublin Poland.
Ann Gastroenterol Surg. 2020 May 25;4(4):343-351. doi: 10.1002/ags3.12344. eCollection 2020 Jul.
Esophageal achalasia is a primary esophageal motility disorder characterized by lack of peristalsis and by incomplete or absent relaxation of the lower esophageal sphincter in response to swallowing. The cause of the disease is unknown. The goal of treatment is to eliminate the functional outflow obstruction at the level of the gastroesophageal junction, therefore allowing emptying of the esophagus into the stomach. They include the laparoscopic Heller myotomy with partial fundoplication, pneumatic dilatation, and peroral endoscopic myotomy. Esophagectomy is considered as a last resort for patients who have failed prior therapeutic attempts. In this evidence and experience-based review, we will illustrate the technique and results of the surgical treatment of esophageal achalasia and compare it to the other available treatment modalities.
贲门失弛缓症是一种原发性食管动力障碍性疾病,其特征为缺乏蠕动,且吞咽时食管下括约肌松弛不完全或无松弛。该病病因不明。治疗目标是消除胃食管交界处的功能性流出道梗阻,从而使食管能够排空至胃内。治疗方法包括腹腔镜下Heller肌切开术加部分胃底折叠术、气囊扩张术和经口内镜下肌切开术。对于先前治疗尝试失败的患者,食管切除术被视为最后的治疗手段。在这篇基于证据和经验的综述中,我们将阐述贲门失弛缓症手术治疗的技术和结果,并将其与其他可用的治疗方式进行比较。