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与抗原呈递B细胞质膜区室相关的内肽酶活性。

Endopeptidase activities associated with the plasma membrane compartment of an antigen-presenting B cell.

作者信息

Chain B M, Bou-Gharios G, Olsen I

机构信息

Department of Biology, University College, London, UK.

出版信息

Clin Exp Immunol. 1989 Jan;75(1):87-92.

Abstract

Endopeptidase activity was characterized in plasma membranes prepared from an antigen-presenting B cell lymphoma, A20. Activity was detected at both neutral and acid pH, and studies with inhibitors confirmed that a number of different enzymes, most probably cysteine, metallo, and aspartic endopeptidases, were associated with the A20 cell surface.

摘要

对从抗原呈递B细胞淋巴瘤A20制备的质膜中的内肽酶活性进行了表征。在中性和酸性pH下均检测到活性,并且用抑制剂进行的研究证实,许多不同的酶,很可能是半胱氨酸、金属和天冬氨酸内肽酶,与A20细胞表面相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecad/1541877/f0561ad79f1b/clinexpimmunol00088-0095-a.jpg

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