Lin Pao-Hwa, Freedland Stephen J
aDepartment of Medicine bUrology Section, Department of Surgery, Durham Veterans Affairs Medical Center and the Duke Prostate Center, Division of Urology, Departments of Surgery and Pathology, Duke University Medical Center, Durham, North Carolina, USA.
Curr Opin Urol. 2015 Jan;25(1):1-5. doi: 10.1097/MOU.0000000000000121.
The primary purpose of this review is to provide an overview of the current evidence linking lifestyle factors and lower urinary tract symptoms (LUTS), and their relevance in men. An extensive literature search from January 2013 to August 2014 was conducted, reviewed, and summarized in conjunction with key prior evidence.
The main findings from this review include 1) epidemiological data repeatedly show a favorable relationship between a healthy eating habits and regular physical activity level and a lower risk for LUTS or progression of LUTS, 2) certain specific nutrients or dietary factors may contribute to the link between diet and LUTS because of their anti-inflammatory potential, and 3) very little research has been conducted to test the epidemiological findings in randomized controlled trials.
Rigorously designed clinical trials are needed to confirm the association between lifestyle factors and LUTS and the effect of lifestyle modification on the development or progression of LUTS. Nevertheless, a healthy lifestyle is known to closely relate with chronic diseases such as cardiovascular disease and diabetes. Thus, promoting a healthy lifestyle with good quality diet and regular physical activity is beneficial not only for potentially improving or reducing LUTS but also for cardiovascular and overall health. Clinicians are encouraged to include healthy lifestyle counseling in their routine care for patients with LUTS.
本综述的主要目的是概述当前将生活方式因素与下尿路症状（LUTS）联系起来的证据，以及它们在男性中的相关性。结合先前的关键证据，对2013年1月至2014年8月期间进行了广泛的文献检索、回顾和总结。
本综述的主要发现包括：1）流行病学数据反复表明，健康的饮食习惯和规律的身体活动水平与LUTS风险降低或LUTS进展之间存在有利关系；2）某些特定营养素或饮食因素因其抗炎潜力可能有助于饮食与LUTS之间的联系；3）在随机对照试验中，很少有研究对流行病学研究结果进行验证。
需要严格设计的临床试验来证实生活方式因素与LUTS之间的关联，以及生活方式改变对LUTS发生或进展的影响。然而，众所周知，健康的生活方式与心血管疾病和糖尿病等慢性疾病密切相关。因此，推广健康的生活方式，包括优质饮食和规律的身体活动，不仅可能有助于改善或减轻LUTS，而且对心血管和整体健康有益。鼓励临床医生在对LUTS患者的常规护理中纳入健康生活方式咨询。
