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纳米比亚儿童癌症发病率:非洲建立登记处的必要性。

Incidence of childhood cancer in Namibia: the need for registries in Africa.

作者信息

Stefan Daniela Cristina, Baadjes Bjorn, Kruger Mariana

机构信息

Department of Paediatrics and Child Health, Stellenbosch University, Cape Town, South Africa.

出版信息

Pan Afr Med J. 2014 Mar 12;17:191. doi: 10.11604/pamj.2014.17.191.3830. eCollection 2014.

DOI:10.11604/pamj.2014.17.191.3830
PMID:25396017
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4228996/
Abstract

INTRODUCTION

Childhood cancer is rare and comprises only 1% of all cancers. The current incidence of childhood cancer in Namibia, as in many other African countries, is not known. The aim of this research was to assess the paediatric cancer incidence between 2003-2010 at Windhoek Central Hospital, the only pediatric oncology-referring centre in Namibia and to compare with the previous calculated incidence in the country 20 years ago.

METHODS

A retrospective, descriptive review of the paediatric oncology cases presenting to Windhoek Central Hospital between 2003 and 2010 was undertaken, and data regarding age, sex, cancer type, area of residence were extrapolated. In this study due to the appearance of the HIV epidemic, an HIV incidence was also calculated.

RESULTS

The incidence rate of all paediatric recorded cancers was 29.4 per million. Leukaemias (22.5%) and retinoblastomas (16.2%) were the most common tumours, with renal tumours, soft tissue sarcomas and lymphomas following in frequency. HIV incidence of children with malignancy was 6.8%.

CONCLUSION

The incidence rates of cancers in this study are remarkably lower compared to a similar study done in the country 20 years ago. Many cancers are still not diagnosed or reported, and others are not treated in the country. The institution of a "twinning programme" between the paediatric haematological/oncological departments in Windhoek and Tygerberg Hospital in Cape Town, South Africa, will contribute to improvement of childhood cancer cases. This twinning programme includes the formation of a cancer registry.

摘要

引言

儿童癌症较为罕见,仅占所有癌症的1%。与许多其他非洲国家一样,纳米比亚目前的儿童癌症发病率尚不清楚。本研究的目的是评估2003年至2010年期间纳米比亚唯一的儿科肿瘤转诊中心温得和克中央医院的儿科癌症发病率,并与该国20年前计算出的发病率进行比较。

方法

对2003年至2010年期间到温得和克中央医院就诊的儿科肿瘤病例进行回顾性描述性分析,并推断出有关年龄、性别、癌症类型、居住地区的数据。在本研究中,由于艾滋病流行的出现,还计算了艾滋病发病率。

结果

所有记录的儿科癌症发病率为每百万29.4例。白血病(22.5%)和成视网膜细胞瘤(16.2%)是最常见的肿瘤,其次是肾肿瘤、软组织肉瘤和淋巴瘤。恶性肿瘤儿童的艾滋病发病率为6.8%。

结论

与20年前在该国进行的类似研究相比,本研究中的癌症发病率显著较低。许多癌症仍未得到诊断或报告,还有一些癌症在该国未得到治疗。温得和克的儿科血液学/肿瘤学部门与南非开普敦的泰格堡医院之间建立的“结对计划”将有助于改善儿童癌症病例。该结对计划包括建立癌症登记处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c7d/4228996/b3683fb35a33/PAMJ-17-191-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c7d/4228996/f04db0bb035d/PAMJ-17-191-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c7d/4228996/b3683fb35a33/PAMJ-17-191-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c7d/4228996/f04db0bb035d/PAMJ-17-191-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c7d/4228996/b3683fb35a33/PAMJ-17-191-g002.jpg

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Cancer control in Africa: which priorities?非洲的癌症控制:哪些优先事项?
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纳米比亚儿科癌症负担:温得和克中央医院收治患者的 10 年回顾性分析队列研究。
PLoS One. 2023 Nov 16;18(11):e0292794. doi: 10.1371/journal.pone.0292794. eCollection 2023.
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