Aithal Sanath, Ganguly Satyaki, Kuruvila Sheela
Department of Dermatology, Venereology and Leprosy, Pondicherry Institute of Medical Sciences, Pondicherry, India.
Indian Dermatol Online J. 2014 Oct;5(4):485-7. doi: 10.4103/2229-5178.142511.
Mucous membrane pemphigoid describes a rare heterogeneous group of chronic, inflammatory, mucous membrane-dominated, subepithelial blistering diseases that manifest a varying constellation of oral, ocular, skin, genital, nasopharyngeal, esophageal, and laryngeal lesions. Life-threatening airway obstruction and sight-threatening ocular scarring can occur in this condition, which is rarely reported in Indian literature. Vitiligo is another acquired autoimmune disorder characterized by loss of melanocytes. Vitiligo is associated with a number of disorders also considered to be autoimmune. Here we report a very rare coexistence of MMP and vitiligo, the first such report from India.
黏膜类天疱疮是一组罕见的异质性慢性炎症性疾病,以黏膜为主,表现为上皮下疱性病变,可出现口腔、眼部、皮肤、生殖器、鼻咽部、食管和喉部等不同部位的病变。这种疾病可导致危及生命的气道阻塞和威胁视力的眼部瘢痕形成,印度文献中对此鲜有报道。白癜风是另一种获得性自身免疫性疾病,其特征是黑素细胞缺失。白癜风还与许多其他被认为是自身免疫性的疾病有关。在此,我们报告了黏膜类天疱疮与白癜风非常罕见的共存病例,这是来自印度的首例此类报告。