Ravljen Mirjam, Bilban Marjan, Kajfež-Bogataj Lučka, Hovelja Tomaž, Vavpotič Damjan
Faculty of Health Sciences, University of Ljubljana, Zdravstvena Pot 5, SI-1000 Ljubljana, Slovenia.
Institute of Occupational Safety, Chengdujska Cesta 25, SI-1260 Ljubljana-Polje, Slovenia.
Int J Environ Res Public Health. 2014 Nov 12;11(11):11616-26. doi: 10.3390/ijerph111111616.
A nationwide study was conducted to explore the short term association between daily individual meteorological parameters and the incidence of acute coronary syndrome (ACS) treated with coronary emergency catheter interventions in the Republic of Slovenia, a south-central European country.
We linked meteorological data with daily ACS incidence for the entire population of Slovenia, for the population over 65 years of age and for the population under 65 years of age. Data were collected daily for a period of 4 years from 1 January 2008 to 31 December 2011. In line with existing studies, we used a main effect generalized linear model with a log-link-function and a Poisson distribution of ACS.
Three of the studied meteorological factors (daily average temperature, atmospheric pressure and relative humidity) all have relevant and significant influences on ACS incidences for the entire population. However, the ACS incidence for the population over 65 is only affected by daily average temperature, while the ACS incidence for the population under 65 is affected by daily average pressure and humidity. In terms of ambient temperature, the overall findings of our study are in line with the findings of the majority of contemporary European studies, which also note a negative correlation. The results regarding atmospheric pressure and humidity are less in line, due to considerable variations in results. Additionally, the number of available European studies on atmospheric pressure and humidity is relatively low. The fourth studied variable-season-does not influence ACS incidence in a statistically significant way.
在欧洲中南部国家斯洛文尼亚共和国开展了一项全国性研究,以探讨每日个体气象参数与接受冠状动脉急诊导管介入治疗的急性冠状动脉综合征(ACS)发病率之间的短期关联。
我们将斯洛文尼亚全体人口、65岁以上人口和65岁以下人口的气象数据与每日ACS发病率相关联。从2008年1月1日至2011年12月31日,为期4年,每天收集数据。与现有研究一致,我们使用了具有对数链接函数和ACS泊松分布的主效应广义线性模型。
所研究的三个气象因素(日平均温度、大气压力和相对湿度)对全体人口的ACS发病率均有相关且显著的影响。然而,65岁以上人群的ACS发病率仅受日平均温度影响,而65岁以下人群的ACS发病率受日平均压力和湿度影响。在环境温度方面,我们研究的总体结果与大多数当代欧洲研究的结果一致,这些研究也指出存在负相关。由于结果差异较大,关于大气压力和湿度的结果不太一致。此外,欧洲关于大气压力和湿度的现有研究数量相对较少。所研究的第四个变量——季节——对ACS发病率没有统计学上的显著影响。