Gancedo Carlos, Flores Carmen-Lisset, Gancedo Juana M
*Department of Metabolism and Cell Signalling. Instituto de Investigaciones Biomédicas "Alberto Sols", CSIC-UAM, Madrid E-28029, Spain.
Biochem Soc Trans. 2014 Dec;42(6):1715-9. doi: 10.1042/BST20140199.
The present article addresses the possibilities offered by yeasts to study the problem of the evolution of moonlighting proteins. It focuses on data available on hexokinase from Saccharomyces cerevisiae that moonlights in catabolite repression and on galactokinase from Kluyveromyces lactis that moonlights controlling the induction of the GAL genes. Possible experimental approaches to studying the evolution of moonlighting hexose kinases are suggested.
本文探讨了酵母在研究兼职蛋白进化问题方面所提供的可能性。它着重于酿酒酵母中参与分解代谢物阻遏的己糖激酶以及乳酸克鲁维酵母中控制GAL基因诱导的半乳糖激酶的现有数据。文中还提出了研究兼职己糖激酶进化的可能实验方法。
