Stacey R Brandon, Caine Augustus J, Hundley W Gregory
Department of Internal Medicine Section on Cardiology, Wake Forest University School of Medicine, Winston-Salem, NC, 27157, USA,
Curr Heart Fail Rep. 2015 Feb;12(1):61-7. doi: 10.1007/s11897-014-0237-1.
Left ventricular (LV) noncompaction cardiomyopathy (LVNC) is a form of cardiomyopathy in which trabeculations fail to "compact" with the left ventricular endocardium during fetal cardiac development and is classically associated with subsequent impairment of LV function, significant mortality, ventricular dysrhythmias, and embolic phenomena. As awareness and medical imaging quality have improved, it is becoming easier to identify trabeculations that traverse the LV cavity and serve as a distinguishing feature of this disorder. Differentiating true noncompaction from mild increases in trabeculations requires prudent imaging and clinical correlation. This review seeks to discuss the potential methods of evaluating left ventricular trabeculations, the role of increased trabeculations in cardiovascular disease, and how their presence may affect clinical management.
左心室(LV)心肌致密化不全心肌病(LVNC)是一种心肌病,在胎儿心脏发育过程中,小梁未能与左心室心内膜“致密化”,通常与随后的左心室功能损害、高死亡率、室性心律失常和栓塞现象相关。随着认识的提高和医学成像质量的改善,识别穿过左心室腔的小梁变得更加容易,这些小梁是这种疾病的一个显著特征。将真正的心肌致密化不全与小梁轻度增加区分开来需要谨慎的成像和临床关联。本综述旨在讨论评估左心室小梁的潜在方法、小梁增加在心血管疾病中的作用以及它们的存在可能如何影响临床管理。