• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Nuclear LC3-positive puncta in stressed cells do not represent autophagosomes.

作者信息

Buckingham Erin M, Carpenter John E, Jackson Wallen, Grose Charles

机构信息

Virology Laboratory, University of Iowa Children's Hospital, Iowa City, IA.

出版信息

Biotechniques. 2014 Nov 1;57(5):241-4. doi: 10.2144/000114226. eCollection 2014 Nov.

DOI:10.2144/000114226
PMID:25399676
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4243465/
Abstract
摘要

相似文献

1
Nuclear LC3-positive puncta in stressed cells do not represent autophagosomes.应激细胞中的核内LC3阳性斑点并不代表自噬体。
Biotechniques. 2014 Nov 1;57(5):241-4. doi: 10.2144/000114226. eCollection 2014 Nov.
2
Biogenesis and cargo selectivity of autophagosomes.自噬体的生物发生和货物选择性。
Annu Rev Biochem. 2011;80:125-56. doi: 10.1146/annurev-biochem-052709-094552.
3
MAP-LC3, a promising autophagosomal marker, is processed during the differentiation and recovery of podocytes from PAN nephrosis.微管相关蛋白轻链3(MAP-LC3)是一种很有前景的自噬体标志物,在嘌呤霉素氨基核苷(PAN)肾病足细胞的分化和恢复过程中会发生加工处理。
FASEB J. 2003 Jun;17(9):1165-7. doi: 10.1096/fj.02-0580fje. Epub 2003 Apr 22.
4
Evidence for fusion between multilamellar endosomes and autophagosomes in HeLa cells.HeLa细胞中多泡体与自噬体之间融合的证据。
Eur J Cell Biol. 1997 Apr;72(4):307-13.
5
Role of Hrs in maturation of autophagosomes in mammalian cells.Hrs在哺乳动物细胞自噬体成熟过程中的作用。
Biochem Biophys Res Commun. 2007 Sep 7;360(4):721-7. doi: 10.1016/j.bbrc.2007.06.105. Epub 2007 Jul 5.
6
Microtubules facilitate autophagosome formation and fusion of autophagosomes with endosomes.微管促进自噬小体的形成以及自噬小体与内体的融合。
Traffic. 2006 Feb;7(2):129-45. doi: 10.1111/j.1600-0854.2005.00368.x.
7
Sequestration of mitotic (M-phase) chromosomes in autophagosomes: mitotic programmed cell death in human Chang liver cells induced by an OH* burst from vanadyl(4).有丝分裂(M期)染色体被隔离于自噬体中:钒酰产生的羟基自由基爆发诱导人张氏肝细胞发生有丝分裂程序性细胞死亡(4) 。
Anat Rec. 1996 May;245(1):1-8. doi: 10.1002/(SICI)1097-0185(199605)245:1<1::AID-AR1>3.0.CO;2-2.
8
Autophagy is involved in the ischemic preconditioning.自噬参与了缺血预处理。
Neurosci Lett. 2009 Feb 13;451(1):16-9. doi: 10.1016/j.neulet.2008.12.019. Epub 2008 Dec 16.
9
Myo1 localizes to phagosomes, some of which traffic to the nucleus in a Myo1-dependent manner in Tetrahymena thermophila.肌球蛋白1定位于吞噬体,在嗜热四膜虫中,其中一些吞噬体以肌球蛋白1依赖的方式运输到细胞核。
Cell Motil Cytoskeleton. 2007 Dec;64(12):926-35. doi: 10.1002/cm.20233.
10
The late stages of autophagy: how does the end begin?自噬的晚期阶段:终点如何开始?
Cell Death Differ. 2009 Jul;16(7):984-90. doi: 10.1038/cdd.2009.54. Epub 2009 May 8.

引用本文的文献

1
Polyclonal LC3B Antibodies Generate Non-Specific Staining in the Nucleus of Herpes Simplex Virus Type 1-Infected Cells: Caution in the Interpretation of LC3 Staining in the Immunofluorescence Analysis of Viral Infections.多克隆LC3B抗体在单纯疱疹病毒1型感染细胞的细胞核中产生非特异性染色:在病毒感染免疫荧光分析中解读LC3染色时需谨慎。
Int J Mol Sci. 2025 Jul 11;26(14):6682. doi: 10.3390/ijms26146682.
2
Fluorescent Protein-Based Autophagy Biosensors.基于荧光蛋白的自噬生物传感器
Materials (Basel). 2021 Jun 2;14(11):3019. doi: 10.3390/ma14113019.
3
Autophagy modulating agents as chemosensitizers for cisplatin therapy in cancer.自噬调节剂作为化疗增敏剂在癌症顺铂治疗中的应用。
Invest New Drugs. 2021 Apr;39(2):538-563. doi: 10.1007/s10637-020-01032-y. Epub 2020 Nov 7.
4
The autophagic protein LC3 translocates to the nucleus and localizes in the nucleolus associated to NUFIP1 in response to cyclic mechanical stress.自噬蛋白LC3会响应周期性机械应力而转位至细胞核,并定位于与NUFIP1相关的核仁中。
Autophagy. 2020 Jul;16(7):1248-1261. doi: 10.1080/15548627.2019.1662584. Epub 2019 Sep 16.
5
Autophagy promotes degradation of polyethyleneimine-alginate nanoparticles in endothelial progenitor cells.自噬促进内皮祖细胞中聚乙烯亚胺-海藻酸盐纳米颗粒的降解。
Int J Nanomedicine. 2017 Sep 7;12:6661-6675. doi: 10.2147/IJN.S141592. eCollection 2017.
6
Standard Immunohistochemical Assays to Assess Autophagy in Mammalian Tissue.评估哺乳动物组织自噬的标准免疫组织化学检测方法。
Cells. 2017 Jun 30;6(3):17. doi: 10.3390/cells6030017.
7
Variable Effects of Autophagy Induction by Trehalose on Herpesviruses Depending on Conditions of Infection.根据感染条件,海藻糖诱导自噬对疱疹病毒的影响各异。
Yale J Biol Med. 2017 Mar 29;90(1):25-33. eCollection 2017 Mar.
8
Development of LC3/GABARAP sensors containing a LIR and a hydrophobic domain to monitor autophagy.用于监测自噬的包含自噬相关区域(LIR)和疏水结构域的LC3/GABARAP传感器的开发。
EMBO J. 2017 Apr 13;36(8):1100-1116. doi: 10.15252/embj.201696315. Epub 2017 Mar 20.
9
Exocytosis of Varicella-Zoster Virus Virions Involves a Convergence of Endosomal and Autophagy Pathways.水痘-带状疱疹病毒颗粒的胞吐作用涉及内体途径和自噬途径的汇聚。
J Virol. 2016 Sep 12;90(19):8673-85. doi: 10.1128/JVI.00915-16. Print 2016 Oct 1.
10
Nuclear LC3 Associates with Slowly Diffusing Complexes that Survey the Nucleolus.核内LC3与缓慢扩散的复合物相关联,这些复合物可监测核仁。
Traffic. 2016 Apr;17(4):369-99. doi: 10.1111/tra.12372. Epub 2016 Feb 18.

本文引用的文献

1
Autophagy proteins regulate ERK phosphorylation.自噬蛋白调节 ERK 磷酸化。
Nat Commun. 2013;4:2799. doi: 10.1038/ncomms3799.
2
Autophagy and the effects of its inhibition on varicella-zoster virus glycoprotein biosynthesis and infectivity.自噬及其对水痘-带状疱疹病毒糖蛋白生物合成和感染力的抑制作用。
J Virol. 2014 Jan;88(2):890-902. doi: 10.1128/JVI.02646-13. Epub 2013 Nov 6.
3
AKT3 controls mitochondrial biogenesis and autophagy via regulation of the major nuclear export protein CRM-1.AKT3 通过调控主要核输出蛋白 CRM-1 控制线粒体生物发生和自噬。
FASEB J. 2014 Jan;28(1):395-407. doi: 10.1096/fj.13-235382. Epub 2013 Sep 30.
4
Visualization and quantitation of abundant macroautophagy in virus-infected cells by confocal three-dimensional fluorescence imaging.通过共聚焦三维荧光成像观察和定量病毒感染细胞中的大量巨自噬。
J Virol Methods. 2013 Oct;193(1):244-50. doi: 10.1016/j.jviromet.2013.06.018. Epub 2013 Jun 20.
5
Herpes simplex virus γ34.5 interferes with autophagosome maturation and antigen presentation in dendritic cells.单纯疱疹病毒 γ34.5 干扰树突状细胞中的自噬体成熟和抗原呈递。
mBio. 2012 Oct 16;3(5):e00267-12. doi: 10.1128/mBio.00267-12.
6
Guidelines for the use and interpretation of assays for monitoring autophagy.自噬监测分析方法的使用和解读指南
Autophagy. 2012 Apr;8(4):445-544. doi: 10.4161/auto.19496.
7
Autophagosome formation during varicella-zoster virus infection following endoplasmic reticulum stress and the unfolded protein response.水痘带状疱疹病毒感染期间内质网应激和未折叠蛋白反应后的自噬体形成。
J Virol. 2011 Sep;85(18):9414-24. doi: 10.1128/JVI.00281-11. Epub 2011 Jul 13.
8
Varicella-zoster virus infection induces autophagy in both cultured cells and human skin vesicles.水痘带状疱疹病毒感染在培养细胞和人皮肤水疱中均诱导自噬。
J Virol. 2009 Jun;83(11):5466-76. doi: 10.1128/JVI.02670-08. Epub 2009 Mar 18.
9
HSV-1 ICP34.5 confers neurovirulence by targeting the Beclin 1 autophagy protein.单纯疱疹病毒1型(HSV-1)的感染细胞蛋白34.5(ICP34.5)通过靶向自噬蛋白Beclin 1赋予神经毒性。
Cell Host Microbe. 2007 Mar 15;1(1):23-35. doi: 10.1016/j.chom.2006.12.001.
10
Cytosolic LC3 ratio as a sensitive index of macroautophagy in isolated rat hepatocytes and H4-II-E cells.胞质LC3比率作为分离的大鼠肝细胞和H4-II-E细胞中巨自噬的敏感指标。
Autophagy. 2007 Nov-Dec;3(6):553-60. doi: 10.4161/auto.4615. Epub 2007 Jun 21.