Ann Intern Med. 2014 Nov 18;161(10 Suppl):S44-52. doi: 10.7326/M13-3001.
Low-value services, such as prescribing brand-name medications that have existing generic equivalents, contribute to unnecessary health care spending.
To evaluate the association of an intervention by using the electronic health record with provider prescription of generic-equivalent medications.
Quasi-experimental study.
General internal medicine (IM) (n = 2) and family medicine (FM) (n = 2) clinics at the University of Pennsylvania from June 2011 to September 2012.
Attending physicians (IM, n = 38; FM, n = 17) and residents (IM, n = 166; FM, n = 34).
In January 2012, the default in the electronic health record was changed for IM providers from displaying brand and generic medications to displaying initially only generics, with the ability to opt out.
Monthly prescriptions of brand-name and generic-equivalent β-blockers, statins, and proton-pump inhibitors.
During the preintervention period, FM providers had slightly higher rates of generic medication prescribing (range, 80.8% to 85.5%) than did IM providers (range, 75.4% to 79.6%), but both groups had similar trends. In the postintervention period relative to the preintervention period, IM providers had an increase in generic prescribing compared with FM providers for all 3 medications combined (5.4 percentage points [95% CI, 2.2 to 8.7 percentage points]; P < 0.001), β-blockers (10.5 percentage points [CI, 5.8 to 15.2 percentage points]; P < 0.001), and statins (4.0 percentage points [CI, 0.4 to 7.6 percentage points]; P = 0.002). Results for proton-pump inhibitors (2.1 percentage points [CI, -3.7 to 8.0 percentage points]; P = 0.47) were not significant. Subset analyses revealed similar findings for attending physicians. Among residents, however, results were imprecise, with wide CIs.
Observational single-center evaluation, comparison groups that represented different specialties, and a small subset of medication classes studied.
The use of default options was an effective method to increase the odds of prescribing generic medication equivalents for β-blockers and statins.
U.S. Department of Veterans Affairs and Robert Wood Johnson Foundation.
开具已有仿制药的品牌药物等低价值服务会导致不必要的医疗保健支出。
评估使用电子病历对医生开具仿制药的影响。
准实验研究。
宾夕法尼亚大学的内科 (IM)(n=38)和家庭医学 (FM)(n=17)诊所,2011 年 6 月至 2012 年 9 月。
主治医生(IM,n=38;FM,n=17)和住院医师(IM,n=166;FM,n=34)。
2012 年 1 月,将 IM 医生电子病历中的默认设置从显示品牌药和仿制药改为仅显示仿制药,可选择查看品牌药。
每月开具的品牌药和仿制药β受体阻滞剂、他汀类药物和质子泵抑制剂的处方数量。
在干预前阶段,FM 医生开具仿制药的比例(80.8%至 85.5%)略高于 IM 医生(75.4%至 79.6%),但两组的趋势相似。在干预后阶段与干预前阶段相比,3 种药物的总体处方中,IM 医生开具仿制药的比例较 FM 医生有所增加(5.4 个百分点 [95%CI,2.2 至 8.7 个百分点];P<0.001),β受体阻滞剂(10.5 个百分点 [CI,5.8 至 15.2 个百分点];P<0.001)和他汀类药物(4.0 个百分点 [CI,0.4 至 7.6 个百分点];P=0.002)。质子泵抑制剂的结果(2.1 个百分点 [CI,-3.7 至 8.0 个百分点];P=0.47)不显著。亚组分析显示主治医生也有类似的发现。然而,在住院医师中,结果不够精确,置信区间较宽。
观察性单中心评估、代表不同专业的比较组以及研究的药物类别较少。
使用默认选项是增加开具β受体阻滞剂和他汀类仿制药的有效方法。
美国退伍军人事务部和罗伯特伍德约翰逊基金会。