Allen E M, Kannan S R, Powell A
J Natl Med Assoc. 1989 Mar;81(3):325-7, 330.
A patient with no known history of primary neoplasia presented with panhypopituitarism secondary to metastasis. Complete anterior pituitary failure was documented by pituitary reserve testing. However, at autopsy there was extensive carcinomatous invasion of the hypothalamus and infundibulum but no adenohypophyseal involvement. The possibility of metastatic disease should be considered in patients presenting with panhypopituitarism. The literature covering this topic is reviewed.
一名无原发性肿瘤病史的患者因转移导致全垂体功能减退。垂体储备功能测试证实存在完全性垂体前叶功能衰竭。然而,尸检发现下丘脑和漏斗部有广泛的癌性浸润,但腺垂体未受累。对于出现全垂体功能减退的患者,应考虑转移性疾病的可能性。本文对涵盖该主题的文献进行了综述。