Abbott Ryan, Ayres Ian, Hui Ed, Hui Ka-Kit
Department of Medicine, Division of General Internal Medicine and Health Services Research, David Geffen School of Medicine at University of California, Los Angeles, CA, USA,
J Gen Intern Med. 2015 Apr;30(4):434-9. doi: 10.1007/s11606-014-3084-6. Epub 2014 Nov 18.
The efficacy of perineal self-acupressure in treating constipation is uncertain.
We aimed to evaluate whether perineal self-acupressure would improve patient reports of quality of life and bowel function at 4 weeks after training.
A randomized, parallel group trial was conducted.
The study took place at the UCLA Department of Medicine.
One hundred adult patients who met Rome III criteria for functional constipation participated.
The control group received information about standard constipation treatment options, while the treatment group received training in perineal self-acupressure plus standard treatment options.
Primary outcome was the Patient Assessment of Constipation Quality of Life (PAC-QOL). Secondary outcomes included patient assessments of bowel function (as measured by a modified Bowel Function Index (BFI)), and health and well-being (as measured by the SF-12v2).
The mean PAC-QOL was improved by 0.76 in the treatment group and by 0.17 in the control group (treatment-effect difference, 0.59 [95 % CI, 0.37 to 0.81]; p < 0.01). The mean modified BFI was improved by 18.1 in the treatment group and by 4.2 in the control group (treatment-effect difference, 13.8 [95 % CI, 5.1 to 22.5]; p < 0.01). The mean SF-12v2 Physical Component Score was improved by 2.69 in the treatment group and reduced by 0.36 in the control group (treatment-effect difference, 3.05, [95 % CI, 0.85 to 5.25]; p < 0.01); and the mean SF-12v2 Mental Component Score was improved by 3.12 in the treatment group and improved by 0.30 in the control group (treatment-effect difference, 2.82, [95 % CI, -0.10 to 5.74]; p < 0.07).
The trial was not blinded.
Among patients with constipation, perineal self-acupressure improves self-reported assessments of quality of life, bowel function, and health and well-being relative to providing standard constipation treatment options alone.
会阴自我按摩治疗便秘的疗效尚不确定。
我们旨在评估会阴自我按摩是否能改善患者在训练4周后报告的生活质量和肠道功能。
进行了一项随机平行组试验。
该研究在加州大学洛杉矶分校医学系进行。
100名符合罗马III型功能性便秘标准的成年患者参与。
对照组接受关于标准便秘治疗方案的信息,而治疗组接受会阴自我按摩训练加标准治疗方案。
主要结局是患者便秘生活质量评估(PAC-QOL)。次要结局包括患者对肠道功能的评估(通过改良的肠道功能指数(BFI)测量)以及健康和幸福感(通过SF-12v2测量)。
治疗组的平均PAC-QOL改善了0.76,对照组改善了0.17(治疗效果差异,0.59 [95%CI,0.37至0.81];p<0.01)。治疗组的平均改良BFI改善了18.1,对照组改善了4.2(治疗效果差异,13.8 [95%CI,5.1至22.5];p<0.01)。治疗组的平均SF-12v2身体成分评分改善了2.69,对照组降低了0.36(治疗效果差异,3.05,[95%CI,0.85至5.25];p<0.01);治疗组的平均SF-12v2精神成分评分改善了3.12,对照组改善了0.30(治疗效果差异,2.82,[95%CI,-0.10至5.74];p<0.07)。
该试验未设盲。
在便秘患者中,相对于仅提供标准便秘治疗方案,会阴自我按摩可改善患者自我报告的生活质量、肠道功能以及健康和幸福感评估。