Eftekharsadat Bina, Ahadi Tannaz, Raissi Gholam Reza, Shakoory Saied Kazem, Fereshtehnejad Seyed Mohammad
1. MD, Physical Medicine and Rehabilitation Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
2. MD, Physical Medicine and Rehabilitation Department, Iran University of Medical Sciences, Tehran, Iran.
Med J Islam Repub Iran. 2014 Jun 14;28:45. eCollection 2014.
Determining the validity of current median sensory nerve conduction techniques for diagnosis of carpal tunnel syndrome (CTS).
Eighty five patients with clinical diagnosis of CTS were compared with the same number of healthy people. The validity of electrodiagnostic tests were compared in a case-control manner. These electrodiagnostic techniques included long-segment, short-segment, 2-segment and relative slowing studies; as well as distoproximal ratio. Receiver Operating Characteristic (ROC) curve employed for comparison, determining the optimal cut-off points for each test. Validity was evaluated with likelihood ratio.
Likelihood ratio (LHR) for Radial-median sensory latency difference was ∞, while LHR for ulnarmedian sensory latency difference was 16.9. Sensitivity of Two-segment method was 98.8% and mixed palmwrist median Nerve Conduction Velocity (NCV) study showed a sensitivity and specificity of 97.6%, 83.5% respectively.
Radial-median latency difference study (optimal cut-off point ≥0.5) and study of wrist-segment NCV (optimal cut-off point <50.45) were the most valuable techniques in diagnosis of CTS, respectively. Median-ulnar latency difference study and disto-proximal ratio study had more diagnostic implication than long and short (mixed) segment technique in this regard.
确定当前正中神经感觉神经传导技术用于诊断腕管综合征（CTS）的有效性。
将85例临床诊断为CTS的患者与相同数量的健康人进行比较。以病例对照的方式比较电诊断测试的有效性。这些电诊断技术包括长节段、短节段、双节段和相对减慢研究；以及远侧与近侧比值。采用受试者操作特征（ROC）曲线进行比较，确定每项测试的最佳截断点。用似然比评估有效性。
桡侧正中感觉潜伏期差异的似然比（LHR）为∞，而尺侧正中感觉潜伏期差异的LHR为16.9。双节段法的敏感性为98.8%，混合手掌-腕部正中神经传导速度（NCV）研究的敏感性和特异性分别为97.6%、83.5%。
桡侧正中潜伏期差异研究（最佳截断点≥0.5）和腕部节段NCV研究（最佳截断点<50.45）分别是诊断CTS最有价值的技术。在这方面，正中-尺侧潜伏期差异研究和远侧与近侧比值研究比长节段和短节段（混合）技术具有更多的诊断意义。
