Taguchi F, Suzuki J, Muranaka M, Anderson N B, Williams R B
Department of Psychosomatic Medicine, Tohoku University Hospital, Sendai.
Tohoku J Exp Med. 1989 Feb;157(2):95-106. doi: 10.1620/tjem.157.95.
Twenty-six healthy young Caucasian males were defined into high hostile (Hi-Ho) group and low hostile (Lo-Ho) group assessed by Cook-Madley's Hostility (Ho) scale. Mental arithmetic task (MA) and forehead cold stimulus task (FCS) were loaded to both Hi-Ho and Lo-Ho groups. Electrocardiographic T-wave amplitude (TWA), heart rate (HR) and coefficient of variance of 100 R-R intervals (CVR-R) were measured continuously during MA and FCS task periods. Greater TWA attenuation was found in Hi-Ho group (p less than 0.05). Although no significant intergroup difference was represented in HR and CVR-R, HR increased significantly (p less than 0.01) in whole subjects and CVR-R was tend to be suppressed during MA period. In addition, comparison of these physiological responses were performed between Type-A and Type-B groups classified by Jenkins' Activity Survey Form-T (JAS-T). There was no significant difference in reactivity of TWA, HR and CVR-R to both two tasks between high and low Type-A scored groups. Previous data suggested that the TWA reactivity in Hi-Ho subjects to cognitive stress showed similar pattern in Type-A individuals. However, autonomic nervous interaction could not be clarified in Hi-Ho subjects. The differentiation of method for assessment of behavioral pattern was also discussed.
26名健康的年轻白种男性根据库克-马德利敌意量表被分为高敌意组（Hi-Ho）和低敌意组（Lo-Ho）。对高敌意组和低敌意组均进行心算任务（MA）和前额冷刺激任务（FCS）。在心算任务和前额冷刺激任务期间，连续测量心电图T波振幅（TWA）、心率（HR）和100个R-R间期的变异系数（CVR-R）。发现高敌意组的TWA衰减更大（p<0.05）。虽然心率和CVR-R在组间无显著差异，但在整个研究对象中心率显著增加（p<0.01），且在心算任务期间CVR-R有被抑制的趋势。此外，对根据詹金斯活动调查问卷-T（JAS-T）分类的A型和B型组之间的这些生理反应进行了比较。高A型得分组和低A型得分组在两项任务中TWA、HR和CVR-R的反应性无显著差异。先前的数据表明，高敌意受试者对认知应激的TWA反应性与A型个体表现出相似的模式。然而，高敌意受试者的自主神经相互作用尚不清楚。还讨论了行为模式评估方法的差异。
