D亚属某些腺病毒血清型的基因组类型分析

Genome type analysis of certain adenovirus serotypes of subgenus D.

作者信息

Adrian T, Wigand R

机构信息

Abteilung für Virologie des Institutes für Medizinische Mikrobiologie und Hygiene, Universitätskliniken, Homburg, Saar.

出版信息

Zentralbl Bakteriol Mikrobiol Hyg A. 1989 Mar;270(4):527-33. doi: 10.1016/s0176-6724(89)80024-0.

DOI:10.1016/s0176-6724(89)80024-0

PMID:2540599

Abstract

The DNA of 19 wild strains of adenovirus types 10 (AV10), 13, 19, 24, and 27 was analysed by five restriction endonucleases (BamHI, BglII, BstEII, HindIII, and SmaI) for their genetic variability and compared with their respective prototypes. Six "AV19a" strains were identical among each other, even with five additional enzymes, but widely different from the prototype. Strains of AV10, 24, and 27 were identical or only slightly different from the respective prototypes. In contrast, three AV13 strains differed in all enzyme patterns from those of the prototype and from one another.

摘要

用五种限制性内切酶（BamHI、BglII、BstEII、HindIII和SmaI）分析了19株10型（AV10）、13型、19型、24型和27型腺病毒野生株的DNA，以研究其遗传变异性，并与各自的原型进行比较。6株“AV19a”毒株彼此相同，即使使用另外五种酶分析也是如此，但与原型差异很大。AV10、24和27型毒株与各自的原型相同或仅有轻微差异。相比之下，3株AV13毒株在所有酶切图谱上均与原型不同，且彼此之间也存在差异。