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Intense immunosuppression for the treatment of an immune reconstitution inflammatory syndrome-like exacerbation after natalizumab withdrawal: a case report.

作者信息

Sepúlveda Maria, Llufriu Sara, Blanco Yolanda, Solà-Valls Nuria, La Puma Delon, Berenguer Joan, Villoslada Pablo, Saiz Albert

机构信息

Center for Neuroimmunology, Service of Neurology, Hospital Clínic and Institut d'Investigació Biomèdica August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Villarroel 170, 08036, Barcelona, Spain.

出版信息

J Neurol. 2015 Jan;262(1):219-21. doi: 10.1007/s00415-014-7574-6. Epub 2014 Nov 20.

DOI:10.1007/s00415-014-7574-6
PMID:25408366
Abstract
摘要

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1
Intense immunosuppression for the treatment of an immune reconstitution inflammatory syndrome-like exacerbation after natalizumab withdrawal: a case report.
J Neurol. 2015 Jan;262(1):219-21. doi: 10.1007/s00415-014-7574-6. Epub 2014 Nov 20.
2
Immune reconstitution inflammatory syndrome and natalizumab-Is it possible before removing the drug?免疫重建炎症综合征与那他珠单抗——在停药前会出现这种情况吗？
Mult Scler Relat Disord. 2014 Sep;3(5):659-61. doi: 10.1016/j.msard.2014.07.001. Epub 2014 Jul 21.
3
Natalizumab-associated cerebellar PML: a case report on how to slow down IRIS.那他珠单抗相关的小脑进行性多灶性白质脑病：关于如何减缓免疫重建炎症综合征的病例报告
J Neurol. 2015;262(4):1055-7. doi: 10.1007/s00415-015-7658-y. Epub 2015 Feb 7.
4
Immune reconstitution inflammatory syndrome after withdrawal of natalizumab?停用那他珠单抗后发生的免疫重建炎症综合征？
Neurology. 2010 Aug 31;75(9):831-3. doi: 10.1212/WNL.0b013e3181f07362.
5
Epstein-Barr virus-associated immune reconstitution inflammatory syndrome as possible cause of fulminant multiple sclerosis relapse after natalizumab interruption.爱泼斯坦-巴尔病毒相关的免疫重建炎症综合征可能是那他珠单抗中断后暴发性多发性硬化复发的原因。
J Neuroimmunol. 2018 Jun 15;319:9-12. doi: 10.1016/j.jneuroim.2018.03.011. Epub 2018 Mar 18.
6
Natalizumab treatment for multiple sclerosis inducing a toxic acute myocardial damage. Is there any relationship?那他珠单抗治疗多发性硬化症引发毒性急性心肌损伤。二者有何关联？
Int J Cardiol. 2016 Mar 1;206:127-8. doi: 10.1016/j.ijcard.2016.01.089. Epub 2016 Jan 8.
7
Immune reconstitution inflammatory syndrome in patients with multiple sclerosis following cessation of natalizumab therapy.那他珠单抗治疗停止后多发性硬化症患者的免疫重建炎症综合征
Arch Neurol. 2011 Feb;68(2):186-91. doi: 10.1001/archneurol.2010.257. Epub 2010 Oct 11.
8
No impact of current therapeutic strategies on disease reactivation after natalizumab discontinuation: a comparative analysis of different approaches during the first year of natalizumab discontinuation.当前治疗策略对那他珠单抗停用后疾病再激活无影响：那他珠单抗停用后第一年不同方法的比较分析
Eur J Neurol. 2015 Mar;22(3):585-7. doi: 10.1111/ene.12487. Epub 2014 Jul 3.
9
Clinical and radiologic rebound after discontinuation of natalizumab therapy in a highly active multiple sclerosis patient was not halted by dimethyl-fumarate: a case report.在一名高度活跃的多发性硬化症患者中，停用那他珠单抗治疗后的临床和影像学反弹未被富马酸二甲酯阻止：病例报告
BMC Neurol. 2015 Dec 7;15:252. doi: 10.1186/s12883-015-0512-0.
10
Long-term safety evaluation of natalizumab for the treatment of multiple sclerosis.那他珠单抗治疗多发性硬化症的长期安全性评估。
Expert Opin Drug Saf. 2017 Aug;16(8):963-972. doi: 10.1080/14740338.2017.1346082. Epub 2017 Jul 5.

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Clinico-radiologic features and therapeutic strategies in tumefactive demyelination: a retrospective analysis of 50 consecutive cases.肿胀性脱髓鞘病变的临床放射学特征及治疗策略：50例连续病例的回顾性分析
Ther Adv Neurol Disord. 2021 May 18;14:17562864211006503. doi: 10.1177/17562864211006503. eCollection 2021.

本文引用的文献

1
No impact of current therapeutic strategies on disease reactivation after natalizumab discontinuation: a comparative analysis of different approaches during the first year of natalizumab discontinuation.当前治疗策略对那他珠单抗停用后疾病再激活无影响：那他珠单抗停用后第一年不同方法的比较分析
Eur J Neurol. 2015 Mar;22(3):585-7. doi: 10.1111/ene.12487. Epub 2014 Jul 3.
2
What to expect after natalizumab cessation in a real-life setting.在真实环境中停用那他珠单抗后的预期情况。
Acta Neurol Scand. 2014 Aug;130(2):97-102. doi: 10.1111/ane.12250. Epub 2014 Apr 10.
3
Fingolimod after natalizumab and the risk of short-term relapse.
那他滨后芬戈莫德和短期复发的风险。
Neurology. 2014 Apr 8;82(14):1204-11. doi: 10.1212/WNL.0000000000000283. Epub 2014 Mar 7.
4
Treatment and prognostic factors for long-term outcome in patients with anti-NMDA receptor encephalitis: an observational cohort study.抗 NMDA 受体脑炎患者的长期预后的治疗和预后因素：一项观察性队列研究。
Lancet Neurol. 2013 Feb;12(2):157-65. doi: 10.1016/S1474-4422(12)70310-1. Epub 2013 Jan 3.
5
Fingolimod reduces recurrence of disease activity after natalizumab withdrawal in multiple sclerosis.芬戈莫德可降低多发性硬化症患者停用那他珠单抗后的疾病活动复发率。
J Neurol. 2013 May;260(5):1382-7. doi: 10.1007/s00415-012-6808-8. Epub 2012 Dec 25.
6
Lethal multiple sclerosis relapse after natalizumab withdrawal.那他珠单抗停药后发生致命性多发性硬化复发。
Neurology. 2012 Nov 27;79(22):2214-6. doi: 10.1212/WNL.0b013e318275979d. Epub 2012 Oct 24.
7
Severe multiple sclerosis reactivation under fingolimod 3 months after natalizumab withdrawal.停用那他珠单抗3个月后，芬戈莫德治疗期间严重多发性硬化症复发。
Mult Scler. 2012 Nov;18(11):1647-9. doi: 10.1177/1352458512458009. Epub 2012 Aug 20.
8
Update on PML and PML-IRIS occurring in multiple sclerosis patients treated with natalizumab.在接受那他珠单抗治疗的多发性硬化症患者中出现的 PML 和 PML-IRIS 的最新进展。
J Neuropathol Exp Neurol. 2012 Jul;71(7):604-17. doi: 10.1097/NEN.0b013e31825caf2c.
9
Pulse monthly steroids during an elective interruption of natalizumab: a post-marketing study.脉冲式每月类固醇治疗在那他珠单抗择期中断期间的应用：一项上市后研究。
Eur J Neurol. 2012 May;19(5):783-7. doi: 10.1111/j.1468-1331.2011.03577.x. Epub 2011 Nov 7.
10
Immune reconstitution inflammatory syndrome in natalizumab-associated PML.与纳武单抗相关的进行性多灶性白质脑病中的免疫重建炎症综合征。
Neurology. 2011 Sep 13;77(11):1061-7. doi: 10.1212/WNL.0b013e31822e55e7. Epub 2011 Aug 10.