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韩国放射技师健康研究:研究设计与基线结果

The radiologic technologists' health study in South Korea: study design and baseline results.

作者信息

Lee Won Jin, Ha Mina, Hwang Seung-sik, Lee Kyoung-Mu, Jin Young-Woo, Jeong Meeseon, Jun Jae Kwan, Cha Eun Shil, Ko Yousun, Choi Kyung-Hwa, Lee Jung-Eun

机构信息

Department of Preventive Medicine, Korea University College of Medicine, Seoul, South Korea,

出版信息

Int Arch Occup Environ Health. 2015 Aug;88(6):759-68. doi: 10.1007/s00420-014-1002-1. Epub 2014 Nov 19.

Abstract

PURPOSE

To describe the study design, methods, and baseline results of a prospective cohort of radiologic technologists which we have initiated in South Korea.

METHODS

The cohort participants were enrolled through a self-administered questionnaire survey administered from April 2012 to May 2013. Survey data were linked with radiation dosimetry, a cancer registry, and health insurance data by personal identification numbers. A nationwide representative survey was also conducted using a stratified random sampling design with face-to-face interviews.

RESULTS

A total of 12,387 radiologic technologists were enrolled, which accounted for approximately 63% of all diagnostic radiologic technologists working in South Korea. For nationwide survey, 585 workers were interviewed using the detailed questionnaire, and buccal cells were also collected by scraping the inside of the cheek. The majority of study subjects were under 50-year-old and male workers. The average annual effective dose of radiation declined both men (from 2.75 to 1.43 mSv) and women (from 1.34 to 0.95 mSv) over the period of 1996-2011. A total of 99 cancers (66 cancers in men and 33 in women) were reported from 1992 to 2010. The standardized incidence ratio of all cancer combined was significantly lower in men (SIR = 0.75, 95% CI 0.58-0.96) than general population, but the ratios for thyroid cancer were significantly higher than expected among both men and women.

CONCLUSIONS

This cohort provides comprehensive information on work activities and health status of diagnostic radiologic technologists. In addition, the nationwide representative sample provides unique opportunities compared with previous radiologic technologist studies.

摘要

目的

描述我们在韩国启动的放射技师前瞻性队列研究的研究设计、方法和基线结果。

方法

队列参与者通过2012年4月至2013年5月进行的自填式问卷调查招募。调查数据通过个人识别号码与辐射剂量测定、癌症登记和健康保险数据相链接。还采用分层随机抽样设计进行了全国代表性调查,并进行了面对面访谈。

结果

共招募了12387名放射技师,约占韩国所有诊断放射技师的63%。在全国性调查中,585名工作人员使用详细问卷接受了访谈,并通过刮取脸颊内侧收集了颊细胞。大多数研究对象为50岁以下男性工作人员。1996 - 2011年期间,男性(从2.75毫希沃特降至1.43毫希沃特)和女性(从1.34毫希沃特降至0.95毫希沃特)的平均年有效辐射剂量均有所下降。1992年至2010年共报告了99例癌症(男性66例,女性33例)。男性所有癌症合并的标准化发病率比(SIR = 0.75,95%可信区间0.58 - 0.96)显著低于一般人群,但甲状腺癌在男性和女性中的发病率均显著高于预期。

结论

该队列提供了关于诊断放射技师工作活动和健康状况的全面信息。此外,与以往的放射技师研究相比,全国代表性样本提供了独特的机会。

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