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巴西哮喘患者的哮喘控制水平及其与药物使用的关系。

Level of asthma control and its relationship with medication use in asthma patients in Brazil.

作者信息

Marchioro Josiane, Gazzotti Mariana Rodrigues, Nascimento Oliver Augusto, Montealegre Federico, Fish James, Jardim José Roberto

机构信息

Paulista School of Medicine, Federal University of São Paulo, São Paulo, Brazil.

出版信息

J Bras Pneumol. 2014 Oct;40(5):487-94. doi: 10.1590/s1806-37132014000500004.

Abstract

OBJECTIVE

To assess asthma patients in Brazil in terms of the level of asthma control, compliance with maintenance treatment, and the use of rescue medication.

METHODS

We used data from a Latin American survey of a total of 400 asthma patients in four Brazilian state capitals, all of whom completed a questionnaire regarding asthma control and treatment.

RESULTS

In that sample, the prevalence of asthma was 8.8%. Among the 400 patients studied, asthma was classified, in accordance with the Global Initiative for Asthma criteria, as controlled, partially controlled, and uncontrolled in 37 (9.3%), 226 (56.5%), and 137 (34.3%), respectively. In those three groups, the proportion of patients on maintenance therapy in the past four weeks was 5.4%, 19.9%, and 41.6%, respectively. The use of rescue medication was significantly more common in the uncontrolled asthma group (86.9%; p < 0.001).

CONCLUSIONS

Our findings suggest that, in accordance with the established international criteria, asthma is uncontrolled in the vast majority of asthma patients in Brazil. Maintenance medications are still underutilized in Brazil, and patients with partially controlled or uncontrolled asthma are more likely to use rescue medications and oral corticosteroids.

摘要

目的

评估巴西哮喘患者的哮喘控制水平、维持治疗依从性及急救药物使用情况。

方法

我们使用了一项拉丁美洲调查的数据,该调查涵盖巴西四个州首府的400名哮喘患者,所有患者均完成了一份关于哮喘控制和治疗的问卷。

结果

在该样本中,哮喘患病率为8.8%。在400名研究患者中,根据全球哮喘防治创议标准,哮喘被分类为控制良好、部分控制和未控制,分别有37名(9.3%)、226名(56.5%)和137名(34.3%)。在这三组中,过去四周接受维持治疗的患者比例分别为5.4%、19.9%和41.6%。急救药物的使用在未控制哮喘组中明显更为常见(86.9%;p<0.001)。

结论

我们的研究结果表明,根据既定的国际标准,巴西绝大多数哮喘患者的哮喘未得到控制。在巴西,维持药物仍未得到充分利用,部分控制或未控制哮喘的患者更有可能使用急救药物和口服糖皮质激素。

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