Kang Young Joong, Ahn Jungho, Hwang Yang-In
Occupational Safety and Health Research Institute, Korea Occupational Safety and Health Agency, 400, Jongga-ro, Jung-gu Ulsan, Republic of Korea.
Gyeonggi Bukbu Area Office, Korea Occupational Safety and Health Agency, 140, Chudong-ro Uijeongbu-si, Gyeonggi-do Republic of Korea.
Ann Occup Environ Med. 2014 Nov 4;26(1):49. doi: 10.1186/s40557-014-0049-5. eCollection 2014.
We report 2 cases of hepatotoxicity in cleanroom workers due to high retained chloroform air concentrations. The women, aged 34 and 41 years, who had been working in a medical endoscopic device manufacturer as cleanroom workers for approximately 40-45 days suffered severe liver damage. Two measured time-weighted averages of the chloroform concentration in the air in the cleanroom were 82.74 and 64.24 ppm, which are more than 6 times the legal occupational exposure limit in Korea. Only 7% of the cleanroom air was newly introduced from outside. The clinical courses of these cases and workplace inspection, led us to conclude that both cases of hepatotoxicity were caused by chloroform exposure.
我们报告了2例洁净室工作人员因空气中氯仿高残留浓度而导致肝毒性的病例。这两名女性，年龄分别为34岁和41岁，她们在一家医疗内窥镜设备制造商担任洁净室工作人员约40 - 45天，均遭受了严重的肝脏损伤。洁净室内空气中氯仿浓度的两个测量时间加权平均值分别为82.74 ppm和64.24 ppm，这超过了韩国法定职业接触限值的6倍以上。洁净室中只有7%的空气是从外部新引入的。这些病例的临床病程及工作场所检查使我们得出结论，这两例肝毒性均由氯仿暴露引起。
