Sadokova I E
Ontogenez. 1989 Jan-Feb;20(1):63-9.
Abnormal cleavage, decrease in the intracellular cAMP and cGMP content and a trend for increase of extracellular cAMP content were observed in sea urchin embryos incubated with KIuR-14 serotoninolytic substance. The addition of serotonin leads to normalization of cleavage and cAMP and cGMP content. It suggests serotonin-specific effect of KIuR-14 and functional relations between serotonin and cyclic nucleotides.
在用KIuR - 14血清素分解物质孵育的海胆胚胎中,观察到异常分裂、细胞内cAMP和cGMP含量降低以及细胞外cAMP含量增加的趋势。添加血清素可使分裂以及cAMP和cGMP含量恢复正常。这表明KIuR - 14具有血清素特异性作用,以及血清素与环核苷酸之间的功能关系。