Shin Saemi, Moon Hyung-Il, Lee Kwon Seob, Hong Mun Ki, Byeon Sang-Hoon
Department of Environmental Health, College of Health Science, Korea University, Seoul 136-703, Korea.
Occupational Safety & Health Research Institute, Korea Occupational Safety & Health Agency, Ulsan 339-30, Korea.
Int J Environ Res Public Health. 2014 Nov 20;11(11):12001-14. doi: 10.3390/ijerph111112001.
This study aimed to devise a method for prioritizing hazardous chemicals for further regulatory action. To accomplish this objective, we chose appropriate indicators and algorithms. Nine indicators from the Globally Harmonized System of Classification and Labeling of Chemicals were used to identify categories to which the authors assigned numerical scores. Exposure indicators included handling volume, distribution, and exposure level. To test the method devised by this study, sixty-two harmful substances controlled by the Occupational Safety and Health Act in Korea, including acrylamide, acrylonitrile, and styrene were ranked using this proposed method. The correlation coefficients between total score and each indicator ranged from 0.160 to 0.641, and those between total score and hazard indicators ranged from 0.603 to 0.641. The latter were higher than the correlation coefficients between total score and exposure indicators, which ranged from 0.160 to 0.421. Correlations between individual indicators were low (-0.240 to 0.376), except for those between handling volume and distribution (0.613), suggesting that each indicator was not strongly correlated. The low correlations between each indicator mean that the indicators and independent and were well chosen for prioritizing harmful chemicals. This method proposed by this study can improve the cost efficiency of chemical management as utilized in occupational regulatory systems.
本研究旨在设计一种方法,对危险化学品进行优先排序,以便采取进一步的监管行动。为实现这一目标,我们选择了合适的指标和算法。采用了全球化学品统一分类和标签制度中的九个指标来确定作者赋予数值分数的类别。暴露指标包括处理量、分布和暴露水平。为了测试本研究设计的方法,使用该提议方法对韩国《职业安全与健康法》管控的62种有害物质(包括丙烯酰胺、丙烯腈和苯乙烯)进行了排名。总分与各指标之间的相关系数在0.160至0.641之间,总分与危害指标之间的相关系数在0.603至0.641之间。后者高于总分与暴露指标之间的相关系数,暴露指标之间的相关系数在0.160至0.421之间。除处理量与分布之间的相关性(0.613)外,各指标之间的相关性较低(-0.240至0.376),这表明各指标之间的相关性不强。各指标之间的低相关性意味着这些指标相互独立,并且在对有害化学品进行优先排序时选择得当。本研究提出的这种方法可以提高职业监管系统中化学品管理的成本效率。