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精神分裂症中的妄想:一项现象学与心理学探索

Delusions in schizophrenia: a phenomenological and psychological exploration.

作者信息

Bentham A M, McKay A P, Quemada I, Clare L, Eastwood N, McKenna P J

出版信息

Cogn Neuropsychiatry. 1996 Nov 1;1(4):289-304. doi: 10.1080/135468096396451.

Abstract

The psychopathological basis of delusions in schizophrenia is poorly understood. The most enduring of several early theories has suggested a causal link with formal thought disorder, whereas recent approaches have proposed relationships with a variety of cognitive abnormalities. The correlations of delusions with other schizophrenic symptoms and with cognitive functions including semantic memory, executive function, and also probabilistic reasoning bias, were examined in a series of (overlapping) groups of 43-79 schizophrenic patients. Delusions were found to be significantly correlated with formal thought disorder, with evidence for a particular link between bizarreness and fragmentariness of delusions and "loosening of association". Delusions were not significantly correlated with overall intellectual function or memory, although there was some suggestion of a complex interaction between delusions, formal thought disorder, and semantic memory impairment. No association between delusions, formal thought disorder, and any measure of executive function was found. Although, as a group, schizophrenic patients showed evidence of probabilistic reasoning bias, this was unrelated to presence and severity of delusions.

摘要

精神分裂症中妄想的心理病理学基础仍未得到充分理解。几种早期理论中最持久的一种认为它与形式思维障碍存在因果联系,而最近的研究方法则提出它与多种认知异常有关。在一系列(相互重叠)由43至79名精神分裂症患者组成的组中,研究了妄想与其他精神分裂症症状以及与包括语义记忆、执行功能以及概率推理偏差在内的认知功能之间的相关性。研究发现,妄想与形式思维障碍显著相关,有证据表明妄想的怪异和碎片化与“联想松弛”之间存在特定联系。妄想与整体智力功能或记忆没有显著相关性,尽管有迹象表明妄想、形式思维障碍和语义记忆损害之间存在复杂的相互作用。未发现妄想、形式思维障碍与任何执行功能指标之间存在关联。尽管作为一个群体,精神分裂症患者表现出概率推理偏差的证据,但这与妄想的存在和严重程度无关。

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