Institut des Sciences et Ingénierie Chimiques, École Polytechnique Fédérale de Lausanne (EPFL).
Angew Chem Int Ed Engl. 2015 Jan 19;54(4):1289-92. doi: 10.1002/anie.201410067. Epub 2014 Nov 24.
A new method for the synthesis of industrially important azoimidazolium dyes is presented. The procedure is based on a reagent which is rarely used in the context of synthetic organic chemistry: nitrous oxide ("laughing gas"). N2O is first coupled to N-heterocyclic carbenes. Subsequent reaction with aromatic compounds through an AlCl3-induced C-H activation process provides azoimidazolium dyes in good yields.
一种新的工业重要偶氮脒盐染料的合成方法被提出。该方法基于一种在合成有机化学中很少使用的试剂：一氧化二氮（“笑气”）。N2O 首先与 N-杂环卡宾偶联，然后通过 AlCl3 诱导的 C-H 活化反应与芳香族化合物反应，以良好的收率得到偶氮脒盐染料。
