具有整体集成分层孔径的微流控平台，用于轻松快速地形成载有货物的囊泡。

Microfluidic platforms with monolithically integrated hierarchical apertures for the facile and rapid formation of cargo-carrying vesicles.

作者信息

Cho Hyesung, Kim Junsoo, Suga Keishi, Ishigami Takaaki, Park Hyunchul, Bang Jung Won, Seo Soonmin, Choi Mansoo, Chang Pahn-Shick, Umakoshi Hiroshi, Jung Ho-Sup, Suh Kahp-Yang

机构信息

Department of Mechanical and Aerospace Engineering, Seoul National University, Seoul, Republic of Korea.

出版信息

Lab Chip. 2015 Jan 21;15(2):373-7. doi: 10.1039/c4lc01096e.

DOI:10.1039/c4lc01096e

PMID:25422046

Abstract

We fabricated a simple yet robust microfluidic platform with monolithically integrated hierarchical apertures. This platform showed efficient diffusive mixing of the introduced lipids through approximately 8000 divisions with tiny pores (~5 μm in diameter), resulting in massive, real-time production of various cargo-carrying particles via multi-hydrodynamic focusing.

摘要

我们制造了一个简单而坚固的微流控平台，该平台具有整体集成的分级孔径。通过约8000次通过微小孔隙（直径约5μm）的分隔，该平台实现了引入脂质的高效扩散混合，从而通过多流体动力学聚焦大量实时生产各种载有货物的颗粒。