Stephens E K, Tauran Y, Coleman A W, Fitzgerald M
Experimental and Regenerative Neurosciences, School of Animal Biology, The University of Western Australia, Crawley, 6009 WA, Australia.
Chem Commun (Camb). 2015 Jan 18;51(5):851-4. doi: 10.1039/c4cc08576k. Epub 2014 Nov 26.
Treatment of neural cells with calix[n]arenes featuring sulphonate moieties and linked to Ag nanoparticles results in reduced reactive species. For Gram+ bacteria there is an inverse correlation between anti-bacterial activity and ROS reduction whereas for Gram- bacteria only calix[6]arenes bearing O-alkyl sulphonate functions act as ROS inhibitors and anti-bacterial agents.
用带有磺酸基团并与银纳米颗粒相连的杯[n]芳烃处理神经细胞会导致活性物质减少。对于革兰氏阳性菌，抗菌活性与活性氧减少之间存在负相关，而对于革兰氏阴性菌，只有带有O-烷基磺酸酯官能团的杯[6]芳烃充当活性氧抑制剂和抗菌剂。
