慈竹叶乙醇提取物中的抗氧化化合物。

Antioxidant compounds from ethanol extracts of bamboo (Neosinocalamus affinis) leaves.

作者信息

Luo Guo-Yong, Luo Ying-Gang, Zhou Rong, Zhou Min, Gu Jian, Ye Qi, Dai Ya, Zhang Guo-Lin

机构信息

a Chengdu Institute of Biology, Chinese Academy of Sciences , Chengdu 610041 , China.

出版信息

J Asian Nat Prod Res. 2015;17(3):248-55. doi: 10.1080/10286020.2014.981164. Epub 2014 Nov 26.

DOI:10.1080/10286020.2014.981164

PMID:25424560

Abstract

Activity-guided fractionation of Neosinocalamus affinis leaves led to obtain two new flavonoids, 4'-O-((7″R,8″S)-8″-guaiacylglyceryl)-pleioside B (9) and apigenin 6-C-β-d-fucopyranosyl-7-O-β-d-glucopyranoside (10) along with eight known compounds. Their structures were elucidated on the basis of spectroscopic data (UV, IR, NMR, and MS). Among these 10 compounds, farobin A (4) and isoorientin (7) showed significant antioxidant activity evaluated by 1,1-diphenyl-2-picrylhydrazyl, 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid), superoxide anion and nitric oxide (NO) radical-scavenging assays.

摘要

对慈竹叶片进行活性导向分离，得到了两种新的黄酮类化合物，4'-O-((7″R,8″S)-8″-愈创木基甘油基)-多花水仙苷B（9）和芹菜素6-C-β-D-岩藻糖基-7-O-β-D-葡萄糖苷（10）以及8种已知化合物。通过光谱数据（紫外、红外、核磁共振和质谱）对它们的结构进行了阐明。在这10种化合物中，远罗滨A（4）和异荭草素（7）通过1,1-二苯基-2-苦基肼、2,2'-偶氮二（3-乙基苯并噻唑啉-6-磺酸）、超氧阴离子和一氧化氮（NO）自由基清除试验显示出显著的抗氧化活性。