Mohamad Hamdan, McNeill Geraldine, Haseen Farhana, N'Dow James, Craig Leone C A, Heys Steven D
a Public Health Nutrition Research Group, School of Medicine and Dentistry , University of Aberdeen , Aberdeen , United Kingdom.
Nutr Cancer. 2015;67(1):43-60. doi: 10.1080/01635581.2015.976313. Epub 2014 Nov 25.
Prostate cancer prognosis may therefore be improved by maintaining healthy weight through diet and physical activity. This systematic review looked at the effect of diet and exercise interventions on body weight among men treated for prostate cancer. MEDLINE, EMBASE, CINAHL, and Cochrane Library databases were searched from the earliest record to August 2013. Randomized controlled trials of diet and exercise interventions in prostate cancer patients that reported body weight or body composition changes were included. A total of 20 trials were included in the review. Because of the heterogeneity of intervention components, a narrative review was conducted. Interventions were categorized as diet (n = 6), exercise (n = 8), or a combination of both diet and exercise (n = 6). The sample size ranged from 8 to 155 and the duration from 3 wk to 4 yr. Four diet interventions and 1 combined diet and exercise intervention achieved significant weight loss with mean values ranging from 0.8 kg to 6.1 kg (median 4.5 kg). Exercise alone did not lead to weight loss, though most of these trials aimed to increase fitness and quality of life rather than decrease body weight. Diet intervention, alone or in combination with exercise, can lead to weight loss in men treated for prostate cancer.
因此，通过饮食和体育活动保持健康体重可能会改善前列腺癌的预后。本系统评价研究了饮食和运动干预对接受前列腺癌治疗的男性体重的影响。检索了MEDLINE、EMBASE、CINAHL和Cochrane图书馆数据库，检索时间从最早记录到2013年8月。纳入了报告体重或身体成分变化的前列腺癌患者饮食和运动干预的随机对照试验。本评价共纳入20项试验。由于干预成分的异质性，进行了叙述性综述。干预措施分为饮食（n = 6）、运动（n = 8）或饮食与运动结合（n = 6）。样本量从8到155不等，持续时间从3周到4年。四项饮食干预和一项饮食与运动结合的干预措施实现了显著的体重减轻，平均值在0.8 kg至6.1 kg之间（中位数为4.5 kg）。单独运动并没有导致体重减轻，尽管这些试验大多旨在提高身体素质和生活质量，而非减轻体重。饮食干预，单独或与运动结合，可导致接受前列腺癌治疗的男性体重减轻。
