Dieckmann Ralf, Schulz Dino, Gosheger Georg, Becker Karsten, Daniilidis Kiriakos, Streitbürger Arne, Hardes Jendrik, Hoell Steffen
Department of Orthopedics and Tumor Orthopedics, Münster University Hospital, Albert-Schweitzer-Campus 1, A1, 48149 Münster, Germany.
BMC Musculoskelet Disord. 2014 Nov 26;15:398. doi: 10.1186/1471-2474-15-398.
Two-stage revision arthroplasty is today regarded as the gold standard treatment method for deep prosthetic joint infection. The aim of the present study was to evaluate clinical and functional outcomes with the Modular Universal Tumor And Revision System (MUTARS) RS stem in patients undergoing two-stage revisions.
The functional and clinical outcomes for 43 patients who had undergone two-stage revision procedures for PJI were analyzed in a retrospective study. The minimum follow-up period was 24 months. Shorter follow-up periods were only observed when there were complications such as loosening or recurrent infection. The mean follow-up period was 3.86 years (range 7 months to 11.6 years).
The success rate with infection control for PJI was 93%. Reinfection occurred in four cases (7%). The risk of reinfection after MRSA infection was 20.5 times greater (P >0.01) than with sensitive or unknown bacteria. Two aseptic loosening occurred after 7 and 20 months. The average Harris Hip Score was 80 (range 62-93).
This retrospective study showed a 93% rate of eradication using specific antibiotic therapy. With the modular MUTARS RS stem, there was a low rate of aseptic loosening of 4.6%. MRSA infection was identified as a risk factor for reinfection. The two-stage procedure with modular cementless implants used is therefore appropriate for treating periprosthetic infections associated with hip endoprostheses.
两阶段翻修关节成形术如今被视为深部人工关节感染的金标准治疗方法。本研究的目的是评估接受两阶段翻修手术的患者使用模块化通用肿瘤与翻修系统(MUTARS)RS柄的临床和功能结果。
在一项回顾性研究中分析了43例因假体周围感染(PJI)接受两阶段翻修手术患者的功能和临床结果。最短随访期为24个月。仅在出现诸如松动或反复感染等并发症时观察到较短的随访期。平均随访期为3.86年(范围7个月至11.6年)。
PJI感染控制成功率为93%。4例(7%)发生再次感染。耐甲氧西林金黄色葡萄球菌(MRSA)感染后再次感染的风险比敏感或不明细菌感染高20.5倍(P>0.01)。7个月和20个月后发生2例无菌性松动。Harris髋关节评分平均为80分(范围62 - 93分)。
这项回顾性研究显示,使用特定抗生素治疗根除率为93%。使用模块化MUTARS RS柄,无菌性松动率低至4.6%。MRSA感染被确定为再次感染的危险因素。因此,采用模块化非骨水泥型植入物的两阶段手术适用于治疗与髋关节假体相关的假体周围感染。