Fujio N, Sakai K, Kinoshita H, Hirohashi K, Kubo S, Iwasa R, Lee K C
World J Surg. 1989 Mar-Apr;13(2):211-7; discussion 217-8. doi: 10.1007/BF01658403.
We retrospectively classified patients with hepatocellular carcinoma by the results of tests of 15-minute indocyanine green retention (ICGR15). Of the 201 patients with hepatocellular carcinoma admitted to our department in the past 6 years, 36 patients were assigned to group 1 (ICGR15 less than 10.0%), 81 patients to group 2 (ICGR15 = 10.1-20.0%), and 84 patients to group 3 (ICGR15 greater than or equal to 20.1%). Of the total 201 patients, 72% underwent liver resection (78% of group 1 patients, 80% of group 2 patients, and 62% of group 3 patients). We regarded the cirrhosis of the patients in group 3 as severe and studied their survival rate classified by the treatment used. Of these 84 patients, 52 patients were treated by liver resection, about half of whom were treated preoperatively by transcatheter arterial embolization (TAE). Another 9 patients were treated preoperatively by both TAE and portal vein embolization (PVE). At 2 years, and again at 3 years, the survival rate was significantly higher when TAE was used preoperatively than with resection alone. We think that the possibility of performing needed liver resection will be enlarged by preoperative PVE and that liver resection can be done more safely after use of PVE in some patients.
我们根据15分钟吲哚菁绿潴留率（ICGR15）检测结果对肝细胞癌患者进行回顾性分类。在过去6年中，我院收治的201例肝细胞癌患者中，36例被归入第1组（ICGR15小于10.0%），81例归入第2组（ICGR15 = 10.1 - 20.0%），84例归入第3组（ICGR15大于或等于20.1%）。在这201例患者中，72%接受了肝切除术（第1组患者中的78%，第2组患者中的80%，第3组患者中的62%）。我们认为第3组患者的肝硬化较为严重，并根据所采用的治疗方法研究了他们的生存率。在这84例患者中，52例接受了肝切除术，其中约一半患者术前接受了经导管动脉栓塞术（TAE）。另外9例患者术前同时接受了TAE和门静脉栓塞术（PVE）。在2年和3年时，术前使用TAE的患者生存率显著高于单纯肝切除术患者。我们认为术前PVE可扩大所需肝切除术的可行性，并且在一些患者中，使用PVE后肝切除术可更安全地进行。
