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葡萄糖耐量作为肝切除患者预后指标的意义。

Significance of glucose tolerance as prognostic sign in hepatectomized patients.

作者信息

Ozawa K, Ida T, Yamada T, Honjo I

出版信息

Am J Surg. 1976 May;131(5):541-6. doi: 10.1016/0002-9610(76)90006-4.

DOI:10.1016/0002-9610(76)90006-4
PMID:179434
Abstract

Glucose tolerance was determined in fourteen patients with cancer of the liver. The patients with parabolic GTT patterns fared relatively better than did those with linear GTT patterns. In the patients with successful extended right hepatectomy, gradually increasing and long-standing hyperglycemia (linear GTT pattern) in response to an oral glucose load was not observed after hepatectomy and the insulin response was significantly greater than that in controls. However, in the patient with unsuccessful extended right hepatectomy, the linear GTT pattern continued for a more prolonged period after hepatectomy.

摘要

对14例肝癌患者进行了葡萄糖耐量测定。葡萄糖耐量试验(GTT)呈抛物线型的患者比呈直线型的患者预后相对较好。在成功进行扩大右肝切除的患者中,肝切除术后未观察到口服葡萄糖负荷后血糖逐渐升高且长期处于高水平(直线型GTT模式),且胰岛素反应明显大于对照组。然而,在扩大右肝切除未成功的患者中,肝切除术后直线型GTT模式持续的时间更长。

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Significance of glucose tolerance as prognostic sign in hepatectomized patients.葡萄糖耐量作为肝切除患者预后指标的意义。
Am J Surg. 1976 May;131(5):541-6. doi: 10.1016/0002-9610(76)90006-4.
2
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引用本文的文献

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Oral glucose tolerance test for preoperative assessment of liver function in liver resection.口服葡萄糖耐量试验用于肝切除术前肝功能评估。
Ann Hepatobiliary Pancreat Surg. 2017 Feb;21(1):1-10. doi: 10.14701/ahbps.2017.21.1.1. Epub 2017 Feb 28.
2
Hepatitis B virus inhibits insulin receptor signaling and impairs liver regeneration via intracellular retention of the insulin receptor.乙肝病毒通过胰岛素受体的细胞内滞留抑制胰岛素受体信号传导并损害肝脏再生。
Cell Mol Life Sci. 2016 Nov;73(21):4121-40. doi: 10.1007/s00018-016-2259-1. Epub 2016 May 7.
3
A prediction scoring system to select the surgical treatment of liver cancer. Further refinement based on 10 years of use.
一种用于选择肝癌手术治疗的预测评分系统。基于10年使用情况的进一步完善。
Ann Surg. 1994 Apr;219(4):342-6. doi: 10.1097/00000658-199404000-00003.
4
Surgical treatment of hepatocellular carcinoma.肝细胞癌的外科治疗
Cancer Chemother Pharmacol. 1994;33 Suppl:S12-7. doi: 10.1007/BF00686661.
5
Prognostic implications of the response of arterial ketone body ratio and insulin secretion to glucose load in major hepatectomy.动脉酮体比值和胰岛素分泌对大肝切除术中葡萄糖负荷反应的预后意义
World J Surg. 1995 Jul-Aug;19(4):603-7; discussion 608. doi: 10.1007/BF00294732.
6
Postoperative liver insufficiency: prevention and management.术后肝功能不全:预防与管理
World J Surg. 1983 Jul;7(4):505-10. doi: 10.1007/BF01655941.
7
Liver resections in cirrhotic patients: a Western experience.
World J Surg. 1986 Apr;10(2):311-7. doi: 10.1007/BF01658152.
8
One hundred hepatic resections. Indications and operative results.一百例肝切除术。手术指征与手术结果。
Ann Surg. 1985 Jul;202(1):42-9. doi: 10.1097/00000658-198507000-00006.
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Results of treatment of patients with hepatocellular carcinoma with severe cirrhosis of the liver.伴有严重肝硬化的肝细胞癌患者的治疗结果。
World J Surg. 1989 Mar-Apr;13(2):211-7; discussion 217-8. doi: 10.1007/BF01658403.
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