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双侧结石继发急性肾损伤的紧急经皮肾镜取石术:对婴儿是否安全有效?

Urgent percutaneous nephrolithotomy for acute kidney injury secondary to bilateral stones: is it safe and effective in infants?

作者信息

Shao Yi, Li Wei-Hua, Hasimu Shayitaji, Shan Dou-Lian, Lu Jun, Xia Shu-Jie

机构信息

Department of Urology, Shanghai First People's Hospital, Shanghai Jiao Tong University, No. 100, Haining Road, Hongkou District, Shanghai, 200080, China.

出版信息

World J Urol. 2015 Sep;33(9):1345-9. doi: 10.1007/s00345-014-1445-8. Epub 2014 Nov 30.

Abstract

PURPOSE

To evaluate the efficacy and safety of urgent percutaneous nephrolithotomy (PNL) for acute kidney injury secondary to bilateral upper urinary stones in infants.

METHODS

A total of seven infants (five boys and two girls), aged from 5 to 12 months, underwent urgent PNL for calculus anuria from September 2011 to March 2013. The initial blood test revealed acute renal injury in all infants. After correcting electrolyte imbalance and acid-base status through medical treatment in a short time without dialysis, all urgent PNL procedures were performed with 16F percutaneous access and small-diameter nephroscopes designed specifically for pediatric surgery on the side with the more dilated pelvis. Stones were fragmented with a pneumatic lithotripter.

RESULTS

Stones were completely removed from the operative side kidneys. The operating time ranged from 35 to 57 min. Blood BUN, serum creatinine, and electrolyte levels returned to normal on postoperative 36 h. There were no major perioperative or postoperative complications and deaths.

CONCLUSIONS

When performed by experienced endourologists, urgent PNL is a safe and effective procedure in infants for acute kidney injury secondary to bilateral upper urinary stones.

摘要

目的

评估急诊经皮肾镜取石术(PNL)治疗婴儿双侧上尿路结石继发急性肾损伤的疗效和安全性。

方法

2011年9月至2013年3月,共有7例年龄在5至12个月的婴儿(5例男孩和2例女孩)因结石性无尿接受急诊PNL治疗。初始血液检查显示所有婴儿均有急性肾损伤。在短时间内通过药物治疗纠正电解质失衡和酸碱状态而未进行透析后,所有急诊PNL手术均采用16F经皮通路,并使用专门为小儿外科设计的小口径肾镜在肾盂扩张更明显的一侧进行。结石用气压弹道碎石机粉碎。

结果

手术侧肾脏结石完全清除。手术时间为35至57分钟。术后36小时血尿素氮、血清肌酐和电解质水平恢复正常。围手术期及术后无重大并发症及死亡病例。

结论

由经验丰富的腔内泌尿外科医生实施时,急诊PNL是治疗婴儿双侧上尿路结石继发急性肾损伤的一种安全有效的方法。

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