Kecioren Training and Research Hospital, Department of Urology, Ankara, Turkey.
Urology. 2012 Sep;80(3):519-23. doi: 10.1016/j.urology.2012.04.018. Epub 2012 Jun 5.
To compare the outcomes of miniaturized percutaneous nephrolithotomy (mini-perc) and retrograde intrarenal surgery (RIRS) in children for 10- to 30-mm renal calculi by evaluating operative data, stone-free rates, and associated complications.
The records of 201 pediatric patients who underwent mini-perc (n = 106) or RIRS (n = 95) for intrarenal stones of 10- to 30-mm size were reviewed retrospectively. The χ(2) test was applied to compare the success rates, postoperative complications, and blood transfusion rates, and the Mann-Whitney U test was used to compare the means of hospital stay, fluoroscopy, and operative time for mini-perc and RIRS.
The stone-free rate was 84.2% for the RIRS group and 85.8% for the mini-perc group after a single procedure (P = .745). These percentages increased to 92.6% and 94.3% with adjunctive therapies for RIRS and mini-perc, respectively. Minor complications classified as Clavien I or II occurred in 17% and 8.4% in mini-perc and RIRS, respectively. No major complications (Clavien III-V) occurred in either group. Overall complication rates in mini-perc were higher, but the differences were not statistically significant (P = .07). However, 7 patients in the mini-perc group received blood transfusions, whereas none of the children in the RIRS group were transfused (P = .015). The mean hospital stay, fluoroscopy, and operation times were significantly longer in the mini-perc group.
This study demonstrates that RIRS is an effective alternative to mini-perc in pediatric patients with intermediate-sized renal stones. Operative time, radiation exposure, hospital stay, and morbidities of percutaneous nephrolithotomy (PNL) can be significantly reduced with the RIRS technique.
通过评估手术数据、结石清除率和相关并发症,比较 10-30mm 肾结石患儿经皮肾镜碎石术(mini-perc)和逆行肾内手术(RIRS)的治疗效果。
回顾性分析 201 例接受 mini-perc(n=106)或 RIRS(n=95)治疗 10-30mm 肾结石的儿童患者的病历资料。采用卡方检验比较两组的成功率、术后并发症发生率和输血率,采用 Mann-Whitney U 检验比较两组的住院时间、透视时间和手术时间。
单次手术的结石清除率在 RIRS 组和 mini-perc 组分别为 84.2%和 85.8%(P=0.745)。对于 RIRS 和 mini-perc,分别采用辅助治疗后,结石清除率分别增加至 92.6%和 94.3%。在 mini-perc 和 RIRS 中,分别有 17%和 8.4%的患者发生轻微并发症(Clavien I 或 II 级)。两组均未发生严重并发症(Clavien III-V 级)。尽管 mini-perc 组的总并发症发生率较高,但差异无统计学意义(P=0.07)。然而,在 mini-perc 组中有 7 名患者接受了输血,而 RIRS 组中没有患者需要输血(P=0.015)。mini-perc 组的平均住院时间、透视时间和手术时间显著更长。
本研究表明,对于患有中等大小肾结石的儿童患者,RIRS 是 mini-perc 的有效替代方法。与 PNL 技术相比,RIRS 技术可显著减少手术时间、辐射暴露、住院时间和并发症。