大鼠组织中α和β维甲酸受体的差异表达。
Differential expression of the alpha and beta retinoic acid receptors in tissues of the rat.
作者信息
Rees J L, Daly A K, Redfern C P
机构信息
Medical Molecular Biology Group, Medical School, University of Newcastle upon Tyne, U.K.
出版信息
Biochem J. 1989 May 1;259(3):917-9. doi: 10.1042/bj2590917.
Abstract
We have compared the expression of alpha and beta retinoic acid receptors (RAR-alpha and RAR-beta) in different rat tissues. The two cDNA probes for RAR-alpha and RAR-beta each specifically detect two different transcripts. RAR-alpha was expressed in all tissues examined, but, in contrast, the expression of RAR-beta was undetectable in some tissues. The data do not support the idea that RAR-beta is specific to epithelial tissues.
摘要
我们比较了不同大鼠组织中α和β视黄酸受体（RAR-α和RAR-β）的表达情况。用于RAR-α和RAR-β的两种cDNA探针各自特异性地检测到两种不同的转录本。RAR-α在所有检测的组织中均有表达，但与之形成对比的是，RAR-β在某些组织中未检测到表达。这些数据不支持RAR-β对上皮组织具有特异性的观点。
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